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Status |
Public on Feb 02, 2016 |
Title |
FinHER trial : Patients with human epidermal growth factor receptor 2 (HER2)–positive breast cancer |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
The FinHER trial is a multicentre phase 3 randomised adjuvant breast cancer trial that enrolled 1010 patients. The women were randomly assigned to receive three cycles of docetaxel or vinorelbine, followed by three cycles of fluorouracil, epirubicin, and cyclophosphamide.
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Overall design |
Of the available Finher HER2 samples, gene mRNA expression data was produced from 202 samples. All samples were re-evaluated to ensure tumour was present in the specimen. RNA was extracted from formalin-fixed, paraffin-embedded (FFPE) primary breast tumour tissue.
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Contributor(s) |
Fumagalli D, Sonnenblick A, Brohée S, Loi S, Desmedt C, Ignatiadis M, Piccart M, Sotiriou C, Jensu H, Neven P, Loible S, Denker C, Lambrecht D |
Citation(s) |
26358523, 26234940 |
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Submission date |
Jan 20, 2015 |
Last update date |
Mar 01, 2023 |
Contact name |
Christos Sotiriou |
E-mail(s) |
christos.sotiriou@hubruxelles.be
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Phone |
+32 2 541 34 57
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Organization name |
Institut Jules Bordet – Université Libre de Bruxelles (ULB)
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Lab |
Breast Cancer Translational Research Laboratory J.C. Heuson (ULB 290)
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Street address |
Rue Meylemeersch 90
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City |
Brussels |
ZIP/Postal code |
1070 |
Country |
Belgium |
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Platforms (1) |
GPL13667 |
[HG-U219] Affymetrix Human Genome U219 Array |
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Samples (203)
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Relations |
BioProject |
PRJNA272973 |