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Status |
Public on Sep 10, 2020 |
Title |
Development of gene expression signatures in the liver cancer cells with FXR overexpression and FXR activation |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
To investigate the role of nuclear receptor FXR during hepatocarcinogenesis, HepG2 cels and SK-Hep-1 cells were transfected with lentiviral mediated FXR overexpressive vector or the negative control. After the cells were treated with FXR agonist GW4064 2uM for 24 h, and total RNA were isolated for detection of gene expression .
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Overall design |
HepG2 cels and SK-Hep-1 cells were transfected with lentiviral mediated FXR overexpressive vector or the negative control. Then the cells were treated with FXR agonist GW4064 2uM for 24 h, and total RNA were isolated for detection of gene expression .
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Contributor(s) |
Huang X, Li N, Zeng Y, Wang X |
Citation |
https://doi.org/10.3892/ol.2020.12022
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Submission date |
Apr 22, 2020 |
Last update date |
Sep 10, 2020 |
Contact name |
xiongfei huang |
E-mail(s) |
15705917895@163.com
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Organization name |
:Fujian mecical university
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Street address |
1 Xue Yuan Road,University Town
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City |
fuzhou |
State/province |
fujian |
ZIP/Postal code |
350122 |
Country |
China |
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Platforms (1) |
GPL13497 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version) |
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Samples (4)
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Relations |
BioProject |
PRJNA627404 |