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Series GSE149111 Query DataSets for GSE149111
Status Public on Sep 10, 2020
Title Development of gene expression signatures in the liver cancer cells with FXR overexpression and FXR activation
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To investigate the role of nuclear receptor FXR during hepatocarcinogenesis, HepG2 cels and SK-Hep-1 cells were transfected with lentiviral mediated FXR overexpressive vector or the negative control. After the cells were treated with FXR agonist GW4064 2uM for 24 h, and total RNA were isolated for detection of gene expression .
 
Overall design HepG2 cels and SK-Hep-1 cells were transfected with lentiviral mediated FXR overexpressive vector or the negative control. Then the cells were treated with FXR agonist GW4064 2uM for 24 h, and total RNA were isolated for detection of gene expression .
 
Contributor(s) Huang X, Li N, Zeng Y, Wang X
Citation https://doi.org/10.3892/ol.2020.12022
Submission date Apr 22, 2020
Last update date Sep 10, 2020
Contact name xiongfei huang
E-mail(s) 15705917895@163.com
Organization name :Fujian mecical university
Street address 1 Xue Yuan Road,University Town
City fuzhou
State/province fujian
ZIP/Postal code 350122
Country China
 
Platforms (1)
GPL13497 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
Samples (4)
GSM4490650 HepG2+ NC +GW
GSM4490651 HepG2+ FXR+GW
GSM4490652 SK-Hep-1 +NC+GW
Relations
BioProject PRJNA627404

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE149111_RAW.tar 8.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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