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    SRL1 Srl1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854421, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SRL1
    Official Full Name
    Srl1p
    Primary source
    SGD:S000005773
    Locus tag
    YOR247W
    See related
    AllianceGenome:SGD:S000005773; FungiDB:YOR247W; VEuPathDB:YOR247W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in fungal-type cell wall organization and nucleobase-containing compound metabolic process. Located in cellular bud tip and fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SRL1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (797676..798308)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene diacylglycerol O-acyltransferase Neighboring gene Env9p Neighboring gene anaphase promoting complex subunit 5 Neighboring gene cleavage polyadenylation factor subunit CLP1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Localization of a subset of yeast mRNAs depends on inheritance of endoplasmic reticulum. Fundakowski J, et al. Traffic, 2012 Dec. PMID 22994588
    2. Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI-anchored mannoproteins. Hagen I, et al. Mol Microbiol, 2004 Jun. PMID 15165243
    3. A role for the Saccharomyces cerevisiae regulation of Ace2 and polarized morphogenesis signaling network in cell integrity. Kurischko C, et al. Genetics, 2005 Oct. PMID 15972461, Free PMC Article
    4. The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1. Kurischko C, et al. J Cell Biol, 2011 Feb 21. PMID 21339329, Free PMC Article
    5. New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae. Vandermeulen MD, et al. Genetics, 2020 Sep. PMID 32665277, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleobase-containing compound metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cellular bud tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Srl1p
    NP_014890.1
    • Mannoprotein that exhibits a tight association with the cell wall; required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants; SRL1 has a paralog, SVS1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      797676..798308
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183666.1 → NP_014890.1  TPA: Srl1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014890.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2U9, Q08673
      UniProtKB/TrEMBL
      A6ZP86, B3LJR6, B5VSC9, C7GWE1, C8ZGZ9, N1NX98
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08673.1

    Gene LinkOut

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