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    CAD1 cinnamyl-alcohol dehydrogenase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843600, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CAD1
    Official Full Name
    cinnamyl-alcohol dehydrogenase
    Primary source
    TAIR:AT1G72680
    Locus tag
    AT1G72680
    See related
    Araport:AT1G72680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCAD1; CINNAMYL ALCOHOL DEHYDROGENASE 1; cinnamyl-alcohol dehydrogenase; F28P22.13; F28P22_13
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    Genomic context

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    See CAD1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (27359109..27361024, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene TRF-like 6 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene IQ-domain 8 Neighboring gene neurofilament heavy protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, sequence analysis and elicitor-/ozone-induced accumulation of cinnamyl alcohol dehydrogenase from Norway spruce (Picea abies L.). Galliano H, et al. Plant Mol Biol, 1993 Oct. PMID 8219046
    2. Expression of cinnamyl alcohol dehydrogenases and their putative homologues during Arabidopsis thaliana growth and development: lessons for database annotations? Kim SJ, et al. Phytochemistry, 2007 Jul. PMID 17467016
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105927.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cinnamyl-alcohol dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lignin biosynthetic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within lignin biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    cinnamyl-alcohol dehydrogenase
    NP_177412.1
    • cinnamyl-alcohol dehydrogenase (CAD1); FUNCTIONS IN: oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, zinc ion binding, cofactor binding; INVOLVED IN: lignin biosynthetic process; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (InterPro:IPR006140), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, zinc-containing, conserved site (InterPro:IPR002328), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: cinnamyl alcohol dehydrogenase homolog 3 (TAIR:AT2G21890.1); Has 36986 Blast hits to 36967 proteins in 3073 species: Archae - 711; Bacteria - 24167; Metazoa - 1364; Fungi - 2774; Plants - 3348; Viruses - 3; Other Eukaryotes - 4619 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27359109..27361024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105927.4 → NP_177412.1  cinnamyl-alcohol dehydrogenase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177412.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9CAI3
      UniProtKB/TrEMBL
      A0A178WLT3, A0A5S9WTU0
      Conserved Domains (1) summary
      cd05283
      Location:12 → 349
      CAD1; Cinnamyl alcohol dehydrogenases (CAD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CAI3.1

    Gene LinkOut

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