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    SIGA sigma factor A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842794, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SIGA
    Official Full Name
    sigma factor A
    Primary source
    TAIR:AT1G64860
    Locus tag
    AT1G64860
    See related
    Araport:AT1G64860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13O11.16; F13O11_16; RNA POLYMERASE SIGMA SUBUNIT 1; RNApolymerase sigma subunit 2; RPOD1; SIG1; SIG2; SIGB; sigma factor A
    Summary
    Subunit of chloroplast RNA polymerase, confers the ability to recognize promoter sequences on the core enzyme
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    Genomic context

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    See SIGA in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (24097736..24100970)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene LOW protein: F-box/kelch-repeat protein (DUF295) Neighboring gene Calcium-binding EF hand family protein Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein S5 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SIG1, a sigma factor for the chloroplast RNA polymerase, differently associates with multiple DNA regions in the chloroplast chromosomes in vivo. Hanaoka M, et al. Int J Mol Sci, 2012 Sep 25. PMID 23202891, Free PMC Article
    2. Sigma factor phosphorylation in the photosynthetic control of photosystem stoichiometry. Shimizu M, et al. Proc Natl Acad Sci U S A, 2010 Jun 8. PMID 20498041, Free PMC Article
    3. Evolutionary rewiring: a modified prokaryotic gene-regulatory pathway in chloroplasts. Puthiyaveetil S, et al. Philos Trans R Soc Lond B Biol Sci, 2013 Jul 19. PMID 23754813, Free PMC Article
    4. Novel nuclear-encoded proteins interacting with a plastid sigma factor, Sig1, in Arabidopsis thaliana. Morikawa K, et al. FEBS Lett, 2002 Mar 13. PMID 11943170
    5. Light induction of Arabidopsis SIG1 and SIG5 transcripts in mature leaves: differential roles of cryptochrome 1 and cryptochrome 2 and dual function of SIG5 in the recognition of plastid promoters. Onda Y, et al. Plant J, 2008 Sep. PMID 18532976

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SIG1 specifically binds to newly identified target promoters as well as to a set of promoters of genes.
      Title: SIG1, a sigma factor for the chloroplast RNA polymerase, differently associates with multiple DNA regions in the chloroplast chromosomes in vivo.
    2. revealed an enhanced phosphorylation of SIG1 under oxidative conditions of plastoquinone in a form associated with the molecular mass of the holoenzyme.
      Title: Sigma factor phosphorylation in the photosynthetic control of photosystem stoichiometry.
    3. Red light induces transcription of SIG1 very strongly, whereas blue light induces transcription of both SIG1 and SIG5.
      Title: Light induction of Arabidopsis SIG1 and SIG5 transcripts in mature leaves: differential roles of cryptochrome 1 and cryptochrome 2 and dual function of SIG5 in the recognition of plastid promoters.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001334181.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sigma factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sigma factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA-templated transcription initiation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in cellular response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to redox state IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in photosystem stoichiometry adjustment IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of RNA biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    sigma factor A
    NP_001319322.1
    • sigma factor A (SIGA); CONTAINS InterPro DOMAIN/s: RNA polymerase sigma factor, region 3/4 (InterPro:IPR013324), RNA polymerase sigma factor, region 2 (InterPro:IPR013325), RNA polymerase sigma-70 region 3 (InterPro:IPR007624), RNA polymerase sigma-70 (InterPro:IPR014284), RNA polymerase sigma-70 factor (InterPro:IPR000943), RNA polymerase sigma-70 region 2 (InterPro:IPR007627); BEST Arabidopsis thaliana protein match is: RNApolymerase sigma subunit 2 (TAIR:AT1G08540.1).
    NP_176666.1
    • sigma factor A (SIGA); CONTAINS InterPro DOMAIN/s: RNA polymerase sigma factor, region 2 (InterPro:IPR013325), Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), RNA polymerase sigma-70 region 3 (InterPro:IPR007624), RNA polymerase sigma-70 (InterPro:IPR014284), RNA polymerase sigma factor, region 3/4 (InterPro:IPR013324), RNA polymerase sigma-70 factor (InterPro:IPR000943), RNA polymerase sigma-70 region 2 (InterPro:IPR007627), RNA polymerase sigma-70 region 4 (InterPro:IPR007630); BEST Arabidopsis thaliana protein match is: RNApolymerase sigma subunit 2 (TAIR:AT1G08540.1); Has 23164 Blast hits to 23156 proteins in 2779 species: Archae - 0; Bacteria - 16620; Metazoa - 0; Fungi - 0; Plants - 234; Viruses - 18; Other Eukaryotes - 6292 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24097736..24100970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105160.3 → NP_176666.1  sigma factor A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176666.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I8A3, O22057, O22576, O24629, Q9FPH1, Q9T0P0
      UniProtKB/TrEMBL
      A0A178W7Q2, A0A5S9WPE8
      Conserved Domains (4) summary
      TIGR02997
      Location:187 → 487
      Sig70-cyanoRpoD; RNA polymerase sigma factor, cyanobacterial RpoD-like family
      pfam04539
      Location:342 → 418
      Sigma70_r3; Sigma-70 region 3
      pfam04542
      Location:263 → 333
      Sigma70_r2; Sigma-70 region 2
      pfam04545
      Location:438 → 487
      Sigma70_r4; Sigma-70, region 4

    2. NM_001334181.1 → NP_001319322.1  sigma factor A [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7Q2, A0A5S9WPE8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O24629.1

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