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    HSL2 HAESA-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836700, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HSL2
    Official Full Name
    HAESA-like 2
    Primary source
    TAIR:AT5G65710
    Locus tag
    AT5G65710
    See related
    Araport:AT5G65710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HAESA-like 2; MPA24.6; MPA24_6
    Summary
    Encodes a protein controlling the separation step of floral organ abscission.
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    Genomic context

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    See HSL2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (26292372..26295687)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene nitrogen fixation S (NIFS)-like 1 Neighboring gene xyloglucan endotransglucosylase/hydrolase 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional profiling of the Arabidopsis abscission mutant hae hsl2 by RNA-Seq. Niederhuth CE, et al. BMC Genomics, 2013 Jan 17. PMID 23327667, Free PMC Article
    2. IDL6-HAE/HSL2 impacts pectin degradation and resistance to Pseudomonas syringae pv tomato DC3000 in Arabidopsis leaves. Wang X, et al. Plant J, 2017 Jan. PMID 27618493
    3. Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence. Kumpf RP, et al. Proc Natl Acad Sci U S A, 2013 Mar 26. PMID 23479623, Free PMC Article
    4. Arabidopsis class I KNOTTED-like homeobox proteins act downstream in the IDA-HAE/HSL2 floral abscission signaling pathway. Shi CL, et al. Plant Cell, 2011 Jul. PMID 21742991, Free PMC Article
    5. Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis. Meng X, et al. Cell Rep, 2016 Feb 16. PMID 26854226, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. HSL2 role in the pectin degradation and resistance to Pseudomonas syringae in Arabidopsis leaves.
      Title: IDL6-HAE/HSL2 impacts pectin degradation and resistance to Pseudomonas syringae pv tomato DC3000 in Arabidopsis leaves.
    2. The study reveals the signaling activation mechanism in floral organ abscission by IDA-induced HAE/HSL2-SERK complex formation accompanied by transphosphorylation.
      Title: Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis.
    3. HAE HSL2-dependent and HAE HSL2-independent changes in genes expression are required for abscission
      Title: Transcriptional profiling of the Arabidopsis abscission mutant hae hsl2 by RNA-Seq.
    4. Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence.
      Title: Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence.
    5. Results indicate that BP/KNAT1 acts as a negative regulator and KNAT2 and KNAT6 act as positive regulators of floral organ separation in the IDA-HAE/HSL2 signaling cascade.
      Title: Arabidopsis class I KNOTTED-like homeobox proteins act downstream in the IDA-HAE/HSL2 floral abscission signaling pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_125968.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lateral root morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf abscission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    HAESA-like 2
    NP_201372.2
    • HAESA-like 2 (HSL2); FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity, ATP binding; INVOLVED IN: transmembrane receptor protein tyrosine kinase signaling pathway, protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: HAESA-like 1 (TAIR:AT1G28440.1); Has 209953 Blast hits to 136246 proteins in 4591 species: Archae - 161; Bacteria - 21175; Metazoa - 62961; Fungi - 10773; Plants - 89081; Viruses - 373; Other Eukaryotes - 25429 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26292372..26295687
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125968.3 → NP_201372.2  HAESA-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201372.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0LGX3, O49544
      UniProtKB/TrEMBL
      A0A5S9YIH4, A0A654GFH4
      Conserved Domains (3) summary
      PLN00113
      Location:36 → 987
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:389 → 412
      LRR_RI; leucine-rich repeat [structural motif]
      cl21453
      Location:692 → 988
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    C0LGX3.1

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