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    XRCC2 homolog of X-ray repair cross complementing 2 (XRCC2) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836573, updated on 18-Sep-2024

    Summary

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    Official Symbol
    XRCC2
    Official Full Name
    homolog of X-ray repair cross complementing 2 (XRCC2)
    Primary source
    TAIR:AT5G64520
    Locus tag
    AT5G64520
    See related
    Araport:AT5G64520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATXRCC2; homolog of X-ray repair cross complementing 2; homolog of X-ray repair cross complementing 2 (XRCC2); MUB3.4; MUB3_4
    Summary
    Encodes a protein of the XRCC2 family involved in DNA repair. atxrcc2-1 Mutants are sensitive to MitomycinC but do not show fertility defects.
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    Genomic context

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    See XRCC2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (25787969..25791197)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene tunicamycin induced protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene xylem NAC domain 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of XRCC2 and RAD51B mutations on somatic and meiotic recombination in Arabidopsis thaliana. Da Ines O, et al. Plant J, 2013 Jun. PMID 23521529
    2. The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis. Bleuyard JY, et al. EMBO J, 2004 Jan 28. PMID 14726957, Free PMC Article
    3. Roles of XRCC2, RAD51B and RAD51D in RAD51-independent SSA recombination. Serra H, et al. PLoS Genet, 2013 Nov. PMID 24278037, Free PMC Article
    4. Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair. Bleuyard JY, et al. Plant J, 2005 Feb. PMID 15686518
    5. Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development. Yamaoka S, et al. Plant Cell, 2013 Aug. PMID 23975897, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001345633.1
    NM_001345634.1
    NM_001345635.1
    NM_001345637.1
    NM_001345638.1
    NM_001345639.1
    NM_001345640.1
    NM_001345641.1
    NM_125848.3
    NM_180937.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent DNA damage sensor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within double-strand break repair via homologous recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rad51B-Rad51C-Rad51D-XRCC2 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in replication fork IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    homolog of X-ray repair cross complementing 2 (XRCC2)
    NP_001318876.1
    • homolog of X-ray repair cross complementing 2 (XRCC2) (XRCC2); Has 186 Blast hits to 186 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 99; Fungi - 44; Plants - 31; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).
    NP_201257.2
    • homolog of X-ray repair cross complementing 2 (XRCC2) (XRCC2); Has 215 Blast hits to 213 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 115; Fungi - 49; Plants - 37; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).
    NP_851268.1
    • homolog of X-ray repair cross complementing 2 (XRCC2) (XRCC2); Has 216 Blast hits to 214 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 116; Fungi - 49; Plants - 37; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25787969..25791197
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345636.1 → NP_001330643.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBH3, A0A5S9YGX0
      Conserved Domains (1) summary
      cd19490
      Location:43 → 305
      XRCC2; XRCC2 recombinase

    2. NM_180937.2 → NP_851268.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851268.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q682D3, Q8GVF2, Q9FLG6
      UniProtKB/TrEMBL
      A0A178UIJ5, A0A5S9YGX0
      Conserved Domains (1) summary
      cd19490
      Location:43 → 299
      XRCC2; XRCC2 recombinase

    3. NM_001345637.1 → NP_001330642.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBF2, A0A5S9YGX0, A0A7G2FJR3
      Conserved Domains (1) summary
      cd19490
      Location:43 → 299
      XRCC2; XRCC2 recombinase

    4. NM_125848.3 → NP_201257.2  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201257.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UKI8, A0A5S9YGX0, F4KDQ6
      Conserved Domains (1) summary
      cd19490
      Location:43 → 299
      XRCC2; XRCC2 recombinase

    5. NM_001345638.1 → NP_001330647.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UJL6, A0A1P8BBG3, A0A384LLW8, A0A5S9YGX0

    6. NM_001345639.1 → NP_001330646.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBI8

    7. NM_001345640.1 → NP_001330649.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBG6

    8. NM_001345641.1 → NP_001330644.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBF9, A0A5S9YGX0, A0A7G2FKH2
      Conserved Domains (1) summary
      cd19490
      Location:43 → 305
      XRCC2; XRCC2 recombinase

    9. NM_001345633.1 → NP_001330648.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBG4, A0A5S9YGX0

    10. NM_001345635.1 → NP_001318876.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2H1ZE99, A0A5S9YGX0
      Conserved Domains (1) summary
      cd19490
      Location:43 → 305
      XRCC2; XRCC2 recombinase

    11. NM_001345634.1 → NP_001330645.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBF0
      Conserved Domains (1) summary
      cd19490
      Location:43 → 299
      XRCC2; XRCC2 recombinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q682D3.2

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