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    MIOX4 myo-inositol oxygenase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828732, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MIOX4
    Official Full Name
    myo-inositol oxygenase 4
    Primary source
    TAIR:AT4G26260
    Locus tag
    AT4G26260
    See related
    Araport:AT4G26260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    myo-inositol oxygenase 4; MYO-INOSITOL OXYGENASE 4; T25K17.70; T25K17_70
    Summary
    Encodes a myo-inositol oxygenase.
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    Genomic context

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    See MIOX4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (13297695..13300444)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene galactinol synthase 6 Neighboring gene ncRNA Neighboring gene phosphofructokinase 3 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots. Siddique S, et al. New Phytol, 2009 Oct. PMID 19691674
    2. Myoinositol oxygenase controls the level of myoinositol in Arabidopsis, but does not increase ascorbic acid. Endres S, et al. Plant Physiol, 2009 Feb. PMID 19091876, Free PMC Article
    3. myo-inositol oxygenase offers a possible entry point into plant ascorbate biosynthesis. Lorence A, et al. Plant Physiol, 2004 Mar. PMID 14976233, Free PMC Article
    4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203915.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inositol oxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-ascorbic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in inositol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within syncytium formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    myo-inositol oxygenase 4
    NP_001190844.1
    • myo-inositol oxygenase 4 (MIOX4); FUNCTIONS IN: inositol oxygenase activity; INVOLVED IN: L-ascorbic acid biosynthetic process, syncytium formation; LOCATED IN: cytoplasm; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF706 (InterPro:IPR007828); BEST Arabidopsis thaliana protein match is: myo-inositol oxygenase 5 (TAIR:AT5G56640.1).
    NP_194356.2
    • myo-inositol oxygenase 4 (MIOX4); FUNCTIONS IN: inositol oxygenase activity; INVOLVED IN: L-ascorbic acid biosynthetic process, syncytium formation; LOCATED IN: cytoplasm; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF706 (InterPro:IPR007828); BEST Arabidopsis thaliana protein match is: myo-inositol oxygenase 5 (TAIR:AT5G56640.1); Has 490 Blast hits to 486 proteins in 159 species: Archae - 0; Bacteria - 27; Metazoa - 132; Fungi - 132; Plants - 97; Viruses - 0; Other Eukaryotes - 102 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13297695..13300444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118759.5 → NP_194356.2  myo-inositol oxygenase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194356.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6XGZ9, Q8H1S0, Q9STQ8
      UniProtKB/TrEMBL
      A0A178V136, A0A7G2F2K2
      Conserved Domains (1) summary
      pfam05153
      Location:67 → 317
      MIOX; Myo-inositol oxygenase

    2. NM_001203915.2 → NP_001190844.1  myo-inositol oxygenase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190844.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V1J3, A0A5S9XW07, A0A7G2F110
      Conserved Domains (1) summary
      pfam05153
      Location:68 → 318
      MIOX; Myo-inositol oxygenase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H1S0.1

    Gene LinkOut

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