U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ILR1 Peptidase M20/M25/M40 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821199, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ILR1
    Official Full Name
    Peptidase M20/M25/M40 family protein
    Primary source
    TAIR:AT3G02875
    Locus tag
    AT3G02875
    See related
    Araport:AT3G02875
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13E7.18; F13E7_18; IAA-AMINO ACID HYDROLASE; IAA-LEUCINE RESISTANT 1
    Summary
    Hydrolyzes amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA), including IAA-Leu and IAA-Phe. Uses Mg and Co ions as cofactors.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ILR1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (631824..634074)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Inositol monophosphatase family protein Neighboring gene ncRNA Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene GAST1 protein homolog 5

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. ILR1, an amidohydrolase that releases active indole-3-acetic acid from conjugates. Bartel B, et al. Science, 1995 Jun 23. PMID 7792599
    2. Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis. LeClere S, et al. J Biol Chem, 2002 Jun 7. PMID 11923288
    3. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help
    NM_111156.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables IAA-Leu conjugate hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables IAA-Phe conjugate hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Peptidase M20/M25/M40 family protein
    NP_186937.1
    • IAA-LEUCINE RESISTANT 1 (ILR1); FUNCTIONS IN: metallopeptidase activity, IAA-Leu conjugate hydrolase activity, IAA-Phe conjugate hydrolase activity; INVOLVED IN: proteolysis, auxin metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M20 (InterPro:IPR002933), Peptidase M20, dimerisation (InterPro:IPR011650), Peptidase M20D, amidohydrolase (InterPro:IPR010168), Peptidase M20D, mername-AA028/carboxypeptidase Ss1 (InterPro:IPR017439); BEST Arabidopsis thaliana protein match is: IAA-leucine resistant (ILR)-like 2 (TAIR:AT5G56660.1); Has 13461 Blast hits to 13451 proteins in 1948 species: Archae - 137; Bacteria - 10103; Metazoa - 64; Fungi - 266; Plants - 279; Viruses - 0; Other Eukaryotes - 2612 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      631824..634074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337440.1 → NP_001325526.1  Peptidase M20/M25/M40 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VFF2, A0A1I9LLI2

    2. NM_001337439.1 → NP_001325525.1  Peptidase M20/M25/M40 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VFF2, A0A1I9LLI1

    3. NM_111156.3 → NP_186937.1  Peptidase M20/M25/M40 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186937.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54968, Q9M8S9
      UniProtKB/TrEMBL
      A0A178VFM1, A0A5S9X8W0, A0A654F537
      Conserved Domains (1) summary
      cd08017
      Location:52 → 427
      M20_IAA_Hyd; M20 Peptidase Indole-3-acetic acid amino acid hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P54968.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.