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    GGPS3 geranylgeranyl pyrophosphate synthase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820681, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GGPS3
    Official Full Name
    geranylgeranyl pyrophosphate synthase 3
    Primary source
    TAIR:AT3G14550
    Locus tag
    AT3G14550
    See related
    Araport:AT3G14550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    geranylgeranyl pyrophosphate synthase 3
    Summary
    Encodes a protein with geranylgeranyl pyrophosphate synthase activity involved in isoprenoid biosynthesis. The enzyme appears to be targeted to the chloroplast in epidermal cells and guard cells of leaves, and in etioplasts in roots.
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    Genomic context

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    See GGPS3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (4884563..4887487, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Terpenoid synthases superfamily protein Neighboring gene Terpenoid cyclases/Protein prenyltransferases superfamily protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene glucan synthase-like 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana isoprenyl diphosphate synthases produce the C25 intermediate geranylfarnesyl diphosphate. Nagel R, et al. Plant J, 2015 Dec. PMID 26505977
    2. Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis. Okada K, et al. Plant Physiol, 2000 Apr. PMID 10759500, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001338122.1
    NM_001338123.1
    NM_112315.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables farnesyltranstransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables geranylfarnesyl diphosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within farnesyl diphosphate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in isoprenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within isoprenoid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in etioplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastoglobule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    geranylgeranyl pyrophosphate synthase 3
    NP_001319550.1
    • geranylgeranyl pyrophosphate synthase 3 (GGPS3); CONTAINS InterPro DOMAIN/s: Polyprenyl synthetase-related (InterPro:IPR017446), Terpenoid synthase (InterPro:IPR008949), Polyprenyl synthetase (InterPro:IPR000092); BEST Arabidopsis thaliana protein match is: Terpenoid synthases superfamily protein (TAIR:AT3G14530.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4884563..4887487 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338122.1 → NP_001319550.1  geranylgeranyl pyrophosphate synthase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IW70, Q38918, Q8GY09, Q8LBX9, Q9LUD9
      UniProtKB/TrEMBL
      A0A1I9LQ60, A0A7G2EI64

    2. NM_001338123.1 → NP_001326728.1  geranylgeranyl pyrophosphate synthase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IW70, Q38918, Q8GY09, Q8LBX9, Q9LUD9
      UniProtKB/TrEMBL
      A0A1I9LQ60, A0A7G2EI64

    3. NM_112315.4 → NP_188073.2  geranylgeranyl pyrophosphate synthase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188073.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IW70, Q38918, Q8GY09, Q8LBX9, Q9LUD9
      UniProtKB/TrEMBL
      A0A1I9LQ60, A0A7G2EI64
      Conserved Domains (1) summary
      COG0142
      Location:65 → 334
      IspA; Geranylgeranyl pyrophosphate synthase [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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