MHX magnesium/proton exchanger [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: MHX
Official Full Name: magnesium/proton exchanger
Primary source: TAIR:AT2G47600
Locus tag: AT2G47600
See related: Araport:AT2G47600
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATMHX; ATMHX1; magnesium/proton exchanger; MAGNESIUM/PROTON EXCHANGER 1; MHX1; T30B22.10
Summary: Encodes a magnesium/proton exchanger, member of putative Na+/Ca2+ antiporter gene family
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

an internal element that considerably increases translational efficiency, without affecting splicing, was identified in the 5' UTR intron of the Arabidopsis thaliana MHX gene.
Title: The Arabidopsis thaliana MHX gene includes an intronic element that boosts translation when localized in a 5' UTR intron.
The upstream open reading frame of AtMHX can inhibit translation but also strongly affect transcript accumulation.
Title: The upstream open reading frame of the Arabidopsis AtMHX gene has a strong impact on transcript accumulation through the nonsense-mediated mRNA decay pathway.
The mechanism of the repression of AtMHX by its untranslated region is described.
Title: Expression of AtMHX, an Arabidopsis vacuolar metal transporter, is repressed by the 5' untranslated region of its gene.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_130328.3

Function	Evidence Code	Pubs
enables calcium:sodium antiporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within iron ion transport	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within magnesium ion transport	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within magnesium ion transport	TAS Traceable Author Statement more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within zinc ion transport	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within zinc ion transport	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in vacuolar membrane	IDA Inferred from Direct Assay more info	PubMed

NP_566105.1

magnesium/proton exchanger (MHX); CONTAINS InterPro DOMAIN/s: Sodium/calcium exchanger membrane region (InterPro:IPR004837); Has 2505 Blast hits to 2112 proteins in 583 species: Archae - 12; Bacteria - 368; Metazoa - 1819; Fungi - 7; Plants - 67; Viruses - 0; Other Eukaryotes - 232 (source: NCBI BLink).