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    GEK1 D-aminoacyl-tRNA deacylase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814906, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GEK1
    Official Full Name
    D-aminoacyl-tRNA deacylase
    Primary source
    TAIR:AT2G03800
    Locus tag
    AT2G03800
    See related
    Araport:AT2G03800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19B11.25; F19B11_25; GEKO1
    Summary
    encodes a D-aminoacyl-tRNA deacylase. Involved in detoxification of D-aminoacyl-tRNA. Mutants also show ethanol-hypersensitive phenotype.
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    Genomic context

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    See GEK1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (1156593..1159138)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Translin family protein Neighboring gene tRNA-Val Neighboring gene 18S pre-ribosomal assembly protein gar2-like protein Neighboring gene nonsense-mediated mRNA decay NMD3 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GEK1, a gene product of Arabidopsis thaliana involved in ethanol tolerance, is a D-aminoacyl-tRNA deacylase. Wydau S, et al. Nucleic Acids Res, 2007. PMID 17251192, Free PMC Article
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GEK1 expression is capable of functionally compensating in E. coli for the absence of endogeneous d-Tyr- tRNA(Tyr) deacylase.
      Title: GEK1, a gene product of Arabidopsis thaliana involved in ethanol tolerance, is a D-aminoacyl-tRNA deacylase.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_126426.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables D-aminoacyl-tRNA deacylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables D-aminoacyl-tRNA deacylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-amino acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to toxic substance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    D-aminoacyl-tRNA deacylase
    NP_178474.2
    • GEKO1 (GEK1); CONTAINS InterPro DOMAIN/s: Uncharacterised conserved protein UCP016210 (InterPro:IPR018033), D-aminoacyl-tRNA deacylase (InterPro:IPR007508); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      1156593..1159138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335203.1 → NP_001325274.1  D-aminoacyl-tRNA deacylase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VUT8, A0A1P8B2P5

    2. NM_126426.5 → NP_178474.2  D-aminoacyl-tRNA deacylase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178474.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQB9, Q76KI8, Q9ZPQ3
      UniProtKB/TrEMBL
      A0A178VUT8, A0A5S9WWZ1
      Conserved Domains (1) summary
      pfam04414
      Location:69 → 311
      tRNA_deacylase; D-aminoacyl-tRNA deacylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZPQ3.2

    Gene LinkOut

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