U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    FBXW8 F-box and WD repeat domain containing 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 787118, updated on 4-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FBXW8provided by VGNC
    Official Full Name
    F-box and WD repeat domain containing 8provided by VGNC
    Primary source
    VGNC:VGNC:58599
    See related
    BGD:BT25536; Ensembl:ENSBTAG00000036183
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FBXW8 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (58026797..58141108, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342621 Neighboring gene F-box protein 21 Neighboring gene voltage-dependent anion-selective channel protein 3-like Neighboring gene tescalcin Neighboring gene cytochrome c oxidase subunit VIIb pseudogene Neighboring gene harakiri, BCL2 interacting protein Neighboring gene ring finger protein, transmembrane 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul7-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    F-box/WD repeat-containing protein 8

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205475.2 → NP_001192404.1  F-box/WD repeat-containing protein 8

      Status: INFERRED

      Source sequence(s)
      NKLS02000017
      UniProtKB/TrEMBL
      A0AAA9SNQ2, E1BGE6
      Related
      ENSBTAP00000047345.4, ENSBTAT00000050675.4
      Conserved Domains (4) summary
      COG2319
      Location:264 → 565
      WD40; WD40 repeat [General function prediction only]
      pfam12937
      Location:119 → 163
      F-box-like; F-box-like
      sd00039
      Location:214 → 253
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:210 → 502
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      58026797..58141108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977500.2 → XP_024833268.1  F-box/WD repeat-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SNQ2
      Conserved Domains (3) summary
      COG2319
      Location:209 → 510
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:159 → 198
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:119 → 142
      F-box-like

    RNA

    1. XR_003029943.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.