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    rps6ka1 ribosomal protein S6 kinase a, polypeptide 1 [ Danio rerio (zebrafish) ]

    Gene ID: 777728, updated on 14-Nov-2024

    Summary

    Official Symbol
    rps6ka1provided by ZNC
    Official Full Name
    ribosomal protein S6 kinase a, polypeptide 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-516
    See related
    Ensembl:ENSDARG00000033437 AllianceGenome:ZFIN:ZDB-GENE-060929-516
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc56h07; zgc:152654
    Summary
    Predicted to enable ribosomal protein S6 kinase activity. Predicted to be involved in TORC1 signaling and positive regulation of DNA-templated transcription. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human RPS6KA1 (ribosomal protein S6 kinase A1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See rps6ka1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (27064414..27171352)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (27143993..27151669)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene claudin 23-like Neighboring gene connector enhancer of kinase suppressor of Ras 1 Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 Neighboring gene E2F transcription factor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribosomal protein S6 kinase alpha-1
    NP_001071243.2
    XP_068070560.1
    XP_068070561.1
    XP_068070562.1
    XP_068070563.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077775.2NP_001071243.2  ribosomal protein S6 kinase alpha-1

      Status: VALIDATED

      Source sequence(s)
      AL935033, BX469900
      Related
      ENSDARP00000144319.1, ENSDART00000178734.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      27064414..27171352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214459.1XP_068070560.1  ribosomal protein S6 kinase alpha-1 isoform X1

    2. XM_068214461.1XP_068070562.1  ribosomal protein S6 kinase alpha-1 isoform X3

      Related
      ENSDARP00000104901.1, ENSDART00000129273.4
    3. XM_068214462.1XP_068070563.1  ribosomal protein S6 kinase alpha-1 isoform X4

    4. XM_068214460.1XP_068070561.1  ribosomal protein S6 kinase alpha-1 isoform X2

      Related
      ENSDARP00000044377.8, ENSDART00000044378.10