papss2a 3'-phosphoadenosine 5'-phosphosulfate synthase 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: papss2aprovided by ZNC
Official Full Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061110-85
See related: Ensembl:ENSDARG00000071021 AllianceGenome:ZFIN:ZDB-GENE-061110-85
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:153748
Summary: Predicted to enable adenylylsulfate kinase activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Orthologous to human PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (23681087..23709263, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (23661063..23689239, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb79e08.x1 (e-PCR)
- UniSTS:191492

fb79e08.x1 (e-PCR)
- UniSTS:191493

fb57f09.x1 (e-PCR)
- UniSTS:190789

fi57f08.x1 (e-PCR)
- UniSTS:197728

fc52g04 (e-PCR)
- UniSTS:189320

fc10e11.x1 (e-PCR)
- UniSTS:192458

fd49e11.y1 (e-PCR)
- UniSTS:195564

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables adenylylsulfate kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenylylsulfate kinase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables sulfate adenylyltransferase (ATP) activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sulfate assimilation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sulfate assimilation	IEA Inferred from Electronic Annotation more info
involved_in sulfate assimilation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077767.1 → NP_001071235.1 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2a

See identical proteins and their annotated locations for NP_001071235.1

Status: PROVISIONAL

Source sequence(s)

BC127397

UniProtKB/TrEMBL

A0JPF3

Related

ENSDARP00000105775.2, ENSDART00000124661.3

Conserved Domains (3) summary

cd00517
Location:241 → 604

ATPS; ATP-sulfurylase

COG0529
Location:13 → 215

CysC; Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]

TIGR00339
Location:223 → 603

sopT; ATP sulphurylase