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    PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 768012, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDHA2provided by VGNC
    Official Full Name
    pyruvate dehydrogenase E1 subunit alpha 2provided by VGNC
    Primary source
    VGNC:VGNC:107249
    See related
    BGD:BT26070; Ensembl:ENSBTAG00000026250
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PDHA2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (28639978..28641315, complement)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene F-box only protein 27 Neighboring gene EKC/KEOPS complex subunit GON7-like Neighboring gene unc-5 netrin receptor C Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene uncharacterized LOC132345563

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Synteny conservation between parts of human chromosome 4q and bovine and ovine chromosomes 6. Lanneluc I, et al. Cytogenet Cell Genet, 1996. PMID 8978779
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC133847

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyruvate dehydrogenase (acetyl-transferring) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetyl-CoA biosynthetic process from pyruvate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
    Names
    pyruvate dehydrogenase (lipoamide) alpha 2
    pyruvate dehydrogenase E1 alpha 2 subunit
    pyruvate dehydrogenase alpha 2
    NP_001070539.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077071.2 → NP_001070539.1  pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

      See identical proteins and their annotated locations for NP_001070539.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111209
      UniProtKB/TrEMBL
      Q2T9Y3
      Related
      ENSBTAP00000037071.4, ENSBTAT00000037234.5
      Conserved Domains (1) summary
      TIGR03182
      Location:59 → 371
      PDH_E1_alph_y; pyruvate dehydrogenase E1 component, alpha subunit

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28639978..28641315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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