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    slc25a21 solute carrier family 25 member 21 [ Danio rerio (zebrafish) ]

    Gene ID: 767694, updated on 12-Sep-2024

    Summary

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    Official Symbol
    slc25a21provided by ZNC
    Official Full Name
    solute carrier family 25 member 21provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-664
    See related
    Ensembl:ENSDARG00000060564 AllianceGenome:ZFIN:ZDB-GENE-060929-664
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153387
    Summary
    Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome. Orthologous to human SLC25A21 (solute carrier family 25 member 21). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See slc25a21 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (38030327..38233021)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (38082742..38285432)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103909058 Neighboring gene pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 Neighboring gene paired box 9 Neighboring gene NK2 transcription factor related, locus 9 (Drosophila)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Imaging Intron Evolution. Panaro MA, et al. Methods Protoc, 2022 Jun 24. PMID 35893579, Free PMC Article
    2. Conservation of Intronic Sequences in Vertebrate Mitochondrial Solute Carrier Genes (Zebrafish, Chicken, Mouse and Human). Calvello R, et al. Noncoding RNA, 2019 Jan 6. PMID 30621336, Free PMC Article
    3. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
    4. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153387

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 2-oxodicarboxylate carrier
    Names
    solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
    solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076632.1 → NP_001070100.1  mitochondrial 2-oxodicarboxylate carrier

      See identical proteins and their annotated locations for NP_001070100.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124342
      UniProtKB/TrEMBL
      Q08C83
      Related
      ENSDARP00000079916.5, ENSDART00000085481.6
      Conserved Domains (2) summary
      PTZ00169
      Location:17 → 288
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:14 → 100
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      38030327..38233021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214456.1 → XP_068070557.1  mitochondrial 2-oxodicarboxylate carrier isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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