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    ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718962, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS8provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 8provided by VGNC
    Primary source
    VGNC:VGNC:69501
    See related
    Ensembl:ENSMMUG00000003300
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS8 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (123053781..123077707, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (123109293..123134695, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 44 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC106993543 Neighboring gene uncharacterized LOC106993532 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      123053781..123077707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015116124.2 → XP_014971610.2  A disintegrin and metalloproteinase with thrombospondin motifs 8

      UniProtKB/TrEMBL
      F7FFM2, G7ND04
      Related
      ENSMMUP00000004390.4, ENSMMUT00000004656.4
      Conserved Domains (6) summary
      smart00209
      Location:528 → 580
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:218 → 425
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:689 → 808
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam01562
      Location:38 → 147
      Pep_M12B_propep; Reprolysin family propeptide
      pfam17771
      Location:439 → 512
      ADAM_CR_2; ADAM cysteine-rich domain
      pfam19030
      Location:835 → 886
      TSP1_ADAMTS; Thrombospondin type 1 domain
    Nucleotide Protein
    Heading Accession and Version

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