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    PTPRC protein tyrosine phosphatase receptor type C [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712657, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PTPRCprovided by VGNC
    Official Full Name
    protein tyrosine phosphatase receptor type Cprovided by VGNC
    Primary source
    VGNC:VGNC:76612
    See related
    Ensembl:ENSMMUG00000000009
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PTPRC in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (56060099..56182800)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (168015818..168138466, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene NIMA related kinase 7 Neighboring gene ATPase H+ transporting V1 subunit G3 Neighboring gene phosphatidylethanolamine-binding protein 1 pseudogene Neighboring gene microRNA mir-181b-1 Neighboring gene microRNA mir-181a-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      56060099..56182800
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015120735.2 → XP_014976221.2  receptor-type tyrosine-protein phosphatase C isoform X3

      UniProtKB/TrEMBL
      F7HTR2
      Conserved Domains (5) summary
      PHA03255
      Location:18 → 161
      PHA03255; BDLF3; Provisional
      cd00063
      Location:331 → 401
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12567
      Location:171 → 232
      CD45; Leukocyte receptor CD45
      cd14557
      Location:645 → 845
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:955 → 1161
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2

    2. XM_015120741.2 → XP_014976227.2  receptor-type tyrosine-protein phosphatase C isoform X4

      UniProtKB/TrEMBL
      A0A5F8AQ76, F7HTR2
      Related
      ENSMMUP00000079230.1, ENSMMUT00000082770.1
      Conserved Domains (5) summary
      PHA03255
      Location:19 → 113
      PHA03255; BDLF3; Provisional
      cd00063
      Location:283 → 353
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12567
      Location:123 → 184
      CD45; Leukocyte receptor CD45
      cd14557
      Location:597 → 797
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:907 → 1113
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2

    3. XM_015120723.2 → XP_014976209.2  receptor-type tyrosine-protein phosphatase C isoform X1

      UniProtKB/TrEMBL
      A0A1D5R142, F7HTR9
      Related
      ENSMMUP00000054026.2, ENSMMUT00000068231.2
      Conserved Domains (6) summary
      cd00063
      Location:397 → 467
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam05109
      Location:52 → 236
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam12453
      Location:7 → 32
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:237 → 298
      CD45; Leukocyte receptor CD45
      cd14557
      Location:711 → 911
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:1021 → 1227
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2

    4. XM_015120730.2 → XP_014976216.2  receptor-type tyrosine-protein phosphatase C isoform X2

      UniProtKB/TrEMBL
      F7HTR9
      Conserved Domains (6) summary
      cd00063
      Location:349 → 419
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12453
      Location:7 → 32
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:189 → 250
      CD45; Leukocyte receptor CD45
      pfam17061
      Location:29 → 182
      PARM
      cd14557
      Location:663 → 863
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:973 → 1179
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2

    5. XM_015120747.2 → XP_014976233.2  receptor-type tyrosine-protein phosphatase C isoform X5

      UniProtKB/TrEMBL
      A0A5F8A543, F7HTR2
      Related
      ENSMMUP00000073006.1, ENSMMUT00000090339.1
      Conserved Domains (5) summary
      cd00063
      Location:236 → 306
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12453
      Location:7 → 32
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:76 → 137
      CD45; Leukocyte receptor CD45
      cd14557
      Location:550 → 750
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:860 → 1066
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2
    Nucleotide Protein
    Heading Accession and Version

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