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    Hsfy2 heat shock transcription factor, Y-linked 2 [ Mus musculus (house mouse) ]

    Gene ID: 71066, updated on 17-Aug-2024

    Summary

    Official Symbol
    Hsfy2provided by MGI
    Official Full Name
    heat shock transcription factor, Y-linked 2provided by MGI
    Primary source
    MGI:MGI:1918316
    See related
    Ensembl:ENSMUSG00000045336 AllianceGenome:MGI:1918316
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hspy2l; 4933413G11Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including HSFY2 (heat shock transcription factor Y-linked 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See Hsfy2 in Genome Data Viewer
    Location:
    1 C1.3; 1 28.72 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (56675203..56676610, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (56636044..56637451, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700003I22 gene Neighboring gene VISTA enhancer mm613 Neighboring gene STARR-seq mESC enhancer starr_00963 Neighboring gene STARR-seq mESC enhancer starr_00964 Neighboring gene predicted gene, 53554 Neighboring gene STARR-seq mESC enhancer starr_00966 Neighboring gene STARR-seq mESC enhancer starr_00967 Neighboring gene STARR-seq mESC enhancer starr_00969 Neighboring gene STARR-seq mESC enhancer starr_00971 Neighboring gene STARR-seq mESC enhancer starr_00972 Neighboring gene STARR-seq mESC enhancer starr_00973 Neighboring gene special AT-rich sequence binding protein 2 Neighboring gene STARR-seq mESC enhancer starr_00974 Neighboring gene RIKEN cDNA 9130024F11 gene Neighboring gene predicted gene, 51624 Neighboring gene STARR-seq mESC enhancer starr_00975

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    heat shock transcription factor, Y-linked
    Names
    heat shock transcription factor, Y linked 2 like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027661.2NP_081937.1  heat shock transcription factor, Y-linked

      See identical proteins and their annotated locations for NP_081937.1

      Status: VALIDATED

      Source sequence(s)
      AC131083, BC049724, CN832499
      Consensus CDS
      CCDS14964.1
      UniProtKB/TrEMBL
      Q80Y37, Q9D449
      Related
      ENSMUSP00000049715.5, ENSMUST00000062085.6
      Conserved Domains (1) summary
      pfam00447
      Location:86194
      HSF_DNA-bind; HSF-type DNA-binding

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      56675203..56676610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)