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    H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710107, updated on 17-Aug-2024

    Summary

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    Official Symbol
    H6PDprovided by VGNC
    Official Full Name
    hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:73340
    Locus tag
    EGK_00198
    See related
    Ensembl:ENSMMUG00000016711
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See H6PD in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (215226291..215257910, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (8406710..8440981)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114674198 Neighboring gene splA/ryanodine receptor domain and SOCS box containing 1 Neighboring gene uncharacterized LOC114674205 Neighboring gene microRNA mir-34a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 6-phosphogluconolactonase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glucose-6-phosphate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt, oxidative branch IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDH/6PGL endoplasmic bifunctional protein
    XP_001099298.2
    XP_015002687.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      215226291..215257910 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147201.2 → XP_015002687.1  GDH/6PGL endoplasmic bifunctional protein isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZPI7, F6VEC2
      Related
      ENSMMUP00000067091.1, ENSMMUT00000109642.1
      Conserved Domains (4) summary
      COG0364
      Location:22 → 504
      Zwf; Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]
      TIGR01198
      Location:556 → 790
      pgl; 6-phosphogluconolactonase
      pfam00479
      Location:29 → 211
      G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain
      pfam02781
      Location:225 → 504
      G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain

    2. XM_001099298.4 → XP_001099298.2  GDH/6PGL endoplasmic bifunctional protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5QL44, F7GGI8
      Related
      ENSMMUP00000048769.2, ENSMMUT00000076904.2
      Conserved Domains (4) summary
      COG0364
      Location:33 → 515
      Zwf; Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]
      TIGR01198
      Location:567 → 801
      pgl; 6-phosphogluconolactonase
      pfam00479
      Location:40 → 222
      G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain
      pfam02781
      Location:236 → 515
      G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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