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    Tm4sf20 transmembrane 4 L six family member 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691066, updated on 17-Aug-2024

    Summary

    Symbol
    Tm4sf20provided by RGD
    Full Name
    transmembrane 4 L six family member 20provided by RGD
    Primary source
    RGD:1588633
    See related
    EnsemblRapid:ENSRNOG00000015460 AllianceGenome:RGD:1588633
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of proteolysis. Predicted to be located in endoplasmic reticulum membrane; focal adhesion; and plasma membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in specific language impairment. Orthologous to human TM4SF20 (transmembrane 4 L six family member 20). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 10.5), Lung (RPKM 6.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tm4sf20 in Genome Data Viewer
    Location:
    9q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (91486847..91500745, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (84038715..84052615, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (88521193..88534710, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene collagen type IV alpha 3 chain Neighboring gene mitochondrial fission factor Neighboring gene uncharacterized LOC120094722 Neighboring gene small cysteine and glycine repeat-containing protein 6-like Neighboring gene uncharacterized LOC120094723

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane 4 L6 family member 20
    Names
    transmembrane 4 L6 family member 20-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109618.1NP_001103088.1  transmembrane 4 L6 family member 20

      See identical proteins and their annotated locations for NP_001103088.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474004
      UniProtKB/TrEMBL
      A6JWB2, D3ZJ15
      Related
      ENSRNOP00000020880.4, ENSRNOT00000020880.7
      Conserved Domains (1) summary
      pfam05805
      Location:2220
      L6_membrane; L6 membrane protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      91486847..91500745 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)