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    Tmem25 transmembrane protein 25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689172, updated on 2-Nov-2024

    Summary

    Official Symbol
    Tmem25provided by RGD
    Official Full Name
    transmembrane protein 25provided by RGD
    Primary source
    RGD:1596132
    See related
    EnsemblRapid:ENSRNOG00000014218 AllianceGenome:RGD:1596132
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of excitatory postsynaptic potential and regulation of protein stability. Predicted to be located in late endosome and lysosome. Orthologous to human TMEM25 (transmembrane protein 25). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 61.6), Kidney (RPKM 46.2) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Tmem25 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (54003907..54009469, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (45107116..45112657, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (49100759..49106258, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology-like domain, family B, member 1 Neighboring gene uncharacterized LOC134480161 Neighboring gene archain 1 Neighboring gene intraflagellar transport 46 Neighboring gene tetratricopeptide repeat domain 36 Neighboring gene lysine methyltransferase 2A Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109528.1NP_001102998.1  transmembrane protein 25 precursor

      See identical proteins and their annotated locations for NP_001102998.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473975
      UniProtKB/TrEMBL
      A0A8I6G802, A6J414
      Related
      ENSRNOP00000077862.2, ENSRNOT00000119805.2
      Conserved Domains (2) summary
      cd00096
      Location:3034
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:27118
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      54003907..54009469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006242960.5XP_006243022.1  transmembrane protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006243022.1

      UniProtKB/TrEMBL
      A0A8I6G802, A6J414
      Conserved Domains (2) summary
      cd00096
      Location:3034
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:27118
      Ig; Immunoglobulin domain
    2. XM_006242959.5XP_006243021.1  transmembrane protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006243021.1

      UniProtKB/TrEMBL
      A0A8I6G802, A6J414
      Conserved Domains (2) summary
      cd00096
      Location:3034
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:27118
      Ig; Immunoglobulin domain