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    Mogat3 monoacylglycerol O-acyltransferase 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685560, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mogat3provided by RGD
    Official Full Name
    monoacylglycerol O-acyltransferase 3provided by RGD
    Primary source
    RGD:1592588
    See related
    AllianceGenome:RGD:1592588
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable 2-acylglycerol O-acyltransferase activity and diacylglycerol O-acyltransferase activity. Predicted to be involved in diacylglycerol biosynthetic process; monoacylglycerol biosynthetic process; and triglyceride biosynthetic process. Predicted to be located in perinuclear endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to several human genes including DGAT2L7P (diacylglycerol O-acyltransferase 2 like 7, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 24.1) See more
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    Genomic context

    See Mogat3 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (25305390..25307024, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (19668703..19669420, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22708622..22710787, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 1 subunit sigma 1 Neighboring gene VGF nerve growth factor inducible Neighboring gene procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 Neighboring gene microRNA 702 Neighboring gene zinc finger, HIT-type containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 2-acylglycerol O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables diacylglycerol O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables diacylglycerol O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in diacylglycerol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in monoacylglycerol biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in triglyceride biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in triglyceride biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P
    Names
    2-acylglycerol O-acyltransferase 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      25305390..25307024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001064308.6XP_001064308.2  putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P

      Conserved Domains (1) summary
      cl17185
      Location:283
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis