U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Slc17a4 solute carrier family 17, member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679784, updated on 14-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Slc17a4provided by RGD
    Official Full Name
    solute carrier family 17, member 4provided by RGD
    Primary source
    RGD:1584758
    See related
    EnsemblRapid:ENSRNOG00000022505 AllianceGenome:RGD:1584758
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable thyroid hormone transmembrane transporter activity and urate transmembrane transporter activity. Predicted to be involved in monoatomic anion transport and sodium-dependent phosphate transport. Predicted to be located in brush border membrane. Predicted to be active in apical plasma membrane. Orthologous to human SLC17A4 (solute carrier family 17 member 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 83.3) and Kidney (RPKM 39.9) See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Slc17a4 in Genome Data Viewer
    Location:
    17p11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (41629417..41646623)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (41201546..41218752)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (43452316..43472192)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100909739 Neighboring gene H2A clustered histone 1 Neighboring gene H2B clustered histone 1 Neighboring gene solute carrier family 17 member 1 Neighboring gene uncharacterized LOC134482855 Neighboring gene solute carrier family 17 member 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables thyroid hormone transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables urate transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium-dependent phosphate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sodium-dependent phosphate transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in thyroid hormone transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in urate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in brush border membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    probable small intestine urate exporter
    Names
    solute carrier family 17 (sodium phosphate), member 4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271214.1 → NP_001258143.1  probable small intestine urate exporter

      See identical proteins and their annotated locations for NP_001258143.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A0G2JXU5, A6KLJ0
      Related
      ENSRNOP00000056253.5, ENSRNOT00000059494.6
      Conserved Domains (1) summary
      cd17318
      Location:40 → 479
      MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      41629417..41646623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008771658.3 → XP_008769880.1  probable small intestine urate exporter isoform X1

      See identical proteins and their annotated locations for XP_008769880.1

      UniProtKB/TrEMBL
      A0A0G2JXU5, A6KLJ0
      Related
      ENSRNOP00000070406.1, ENSRNOT00000088939.3
      Conserved Domains (1) summary
      cd17318
      Location:40 → 479
      MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

    2. XM_039096055.1 → XP_038951983.1  probable small intestine urate exporter isoform X2

      UniProtKB/TrEMBL
      D3ZX83
      Conserved Domains (1) summary
      cl28910
      Location:40 → 401
      MFS; Major Facilitator Superfamily

    3. XM_039096054.2 → XP_038951982.1  probable small intestine urate exporter isoform X1

      UniProtKB/TrEMBL
      A0A0G2JXU5, A6KLJ0
      Conserved Domains (1) summary
      cd17318
      Location:40 → 479
      MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

    4. XM_008771659.4 → XP_008769881.1  probable small intestine urate exporter isoform X1

      See identical proteins and their annotated locations for XP_008769881.1

      UniProtKB/TrEMBL
      A0A0G2JXU5, A6KLJ0
      Conserved Domains (1) summary
      cd17318
      Location:40 → 479
      MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

    5. XM_039096056.1 → XP_038951984.1  probable small intestine urate exporter isoform X3

      Conserved Domains (1) summary
      TIGR00894
      Location:12 → 293
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools