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    TP53TG3C TP53 target 3C [ Homo sapiens (human) ]

    Gene ID: 653550, updated on 10-Oct-2024

    Summary

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    Official Symbol
    TP53TG3Cprovided by HGNC
    Official Full Name
    TP53 target 3Cprovided by HGNC
    Primary source
    HGNC:HGNC:42962
    See related
    Ensembl:ENSG00000205457 AllianceGenome:HGNC:42962
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TP53TG3; TP53TG3E; TP53TG3F
    Summary
    Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis (RPKM 7.4), placenta (RPKM 0.6) and 2 other tissues See more
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    Genomic context

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    See TP53TG3C in Genome Data Viewer
    Location:
    16p11.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (33192510..33196858)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (33205547..33208179)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene COX assembly mitochondrial protein 2 homolog Neighboring gene ABHD17A pseudogene 9 Neighboring gene uncharacterized LOC124903683 Neighboring gene TP53 target 3 family member E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of a novel TP53-inducible gene, TP53TG3. Ng CC, et al. Genes Chromosomes Cancer, 1999 Dec. PMID 10534768
    2. Identification of genes related to Parkinson's disease using expressed sequence tags. Kim JM, et al. DNA Res, 2006 Dec 31. PMID 17213182
    3. Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. Vichas A, et al. Nat Commun, 2021 Aug 9. PMID 34373451, Free PMC Article
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC119888

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TP53-target gene 3 protein
    Names
    TP53-inducible gene 3 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205259.3 → NP_001192188.1  TP53-target gene 3 protein

      See identical proteins and their annotated locations for NP_001192188.1

      Status: VALIDATED

      Source sequence(s)
      AC138869
      Consensus CDS
      CCDS58458.1
      UniProtKB/Swiss-Prot
      B2R5K6, Q4KN31, Q9ULY9, Q9ULZ0
      Related
      ENSP00000455132.1, ENST00000561509.3

    RNA

    1. NR_110914.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC138869

    2. NR_158182.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC138869

    3. NR_158183.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC138869

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      33192510..33196858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047434515.1 → XP_047290471.1  TP53-target gene 3 protein isoform X3

      Related
      ENSP00000353397.2, ENST00000360260.6

    2. XM_011545920.2 → XP_011544222.1  TP53-target gene 3 protein isoform X2

      See identical proteins and their annotated locations for XP_011544222.1

      UniProtKB/Swiss-Prot
      Q9ULZ0
      Related
      ENSP00000457790.1, ENST00000569719.5

    3. XM_017023591.2 → XP_016879080.1  TP53-target gene 3 protein isoform X1

      UniProtKB/TrEMBL
      I3L219

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001205260.1: Suppressed sequence

      Description
      NM_001205260.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ULZ0.2 GenPept UniProtKB/Swiss-Prot:Q9ULZ0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials