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    Defb26 defensin beta 26 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 641629, updated on 17-Aug-2024

    Summary

    Symbol
    Defb26provided by RGD
    Full Name
    defensin beta 26provided by RGD
    Primary source
    RGD:1564413
    See related
    EnsemblRapid:ENSRNOG00000053114 AllianceGenome:RGD:1564413
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB125 (defensin beta 125). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See Defb26 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (161437500..161441234, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (140977214..140980949, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (147982213..147985616, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene defensin beta 20 Neighboring gene defensin beta 22 Neighboring gene defensin beta 28 Neighboring gene ribosomal protein S10, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    beta-defensin 125
    Names
    beta-defensin 125-like
    beta-defensin 26

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037506.2NP_001032595.1  beta-defensin 125 precursor

      See identical proteins and their annotated locations for NP_001032595.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      C8CKX5, Q32ZG6
      Related
      ENSRNOP00000071709.1, ENSRNOT00000087431.3
      Conserved Domains (1) summary
      pfam13841
      Location:2858
      Defensin_beta_2; Beta defensin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      161437500..161441234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)