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    AURKC aurora kinase C [ Bos taurus (domestic cattle) ]

    Gene ID: 618599, updated on 4-Oct-2024

    Summary

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    Gene symbol
    AURKC
    Gene description
    aurora kinase C
    See related
    BGD:BT24009
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See AURKC in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (64448917..64458059)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene zinc finger imprinted 3 Neighboring gene double homeobox A Neighboring gene zinc finger protein 805 Neighboring gene zinc finger protein 543 Neighboring gene zinc finger protein 304

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatio-temporal expression patterns of aurora kinases a, B, and C and cytoplasmic polyadenylation-element-binding protein in bovine oocytes during meiotic maturation. Uzbekova S, et al. Biol Reprod, 2008 Feb. PMID 17687118
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AURKB, AURKC, and Thr-phosphorylated AURKA were detected at a contractile ring/midbody during the first polar body extrusion.
      Title: Spatio-temporal expression patterns of aurora kinases a, B, and C and cytoplasmic polyadenylation-element-binding protein in bovine oocytes during meiotic maturation.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromosome passenger complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle midzone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aurora kinase C
    NP_001180124.1
    XP_005219854.1
    XP_005219855.1
    XP_059732965.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193195.1 → NP_001180124.1  aurora kinase C

      See identical proteins and their annotated locations for NP_001180124.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      Conserved Domains (2) summary
      smart00220
      Location:38 → 288
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:31 → 299
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      64448917..64458059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005219798.4 → XP_005219855.1  aurora kinase C isoform X3

      Conserved Domains (2) summary
      smart00220
      Location:37 → 287
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:30 → 298
      PKc_like; Protein Kinases, catalytic domain

    2. XM_059876982.1 → XP_059732965.1  aurora kinase C isoform X1

    3. XM_005219797.5 → XP_005219854.1  aurora kinase C isoform X2

      See identical proteins and their annotated locations for XP_005219854.1

      Conserved Domains (2) summary
      smart00220
      Location:37 → 287
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:30 → 298
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

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