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    GRIK2 glutamate ionotropic receptor kainate type subunit 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 615226, updated on 10-Oct-2024

    Summary

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    Official Symbol
    GRIK2provided by VGNC
    Official Full Name
    glutamate ionotropic receptor kainate type subunit 2provided by VGNC
    Primary source
    VGNC:VGNC:29643
    See related
    BGD:BT15169; Ensembl:ENSBTAG00000033153
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See GRIK2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (47887699..48618731, complement)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2-like Neighboring gene uncharacterized LOC112448128 Neighboring gene large ribosomal subunit protein uL22-like Neighboring gene activating signal cointegrator 1 complex subunit 3 Neighboring gene transfer RNA cysteine (anticodon GCA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kainate selective glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of kainate selective glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor ionotropic, kainate 2
    Names
    glutamate receptor, ionotropic, kainate 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193063.1 → NP_001179992.1  glutamate receptor ionotropic, kainate 2

      See identical proteins and their annotated locations for NP_001179992.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000009
      UniProtKB/TrEMBL
      A0A3Q1LHV2, A0A3Q1LR33
      Related
      ENSBTAP00000058422.2, ENSBTAT00000082592.2
      Conserved Domains (2) summary
      cd06382
      Location:37 → 414
      PBP1_iGluR_Kainate; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the kainate receptors
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      47887699..48618731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024996836.2 → XP_024852604.1  glutamate receptor ionotropic, kainate 2 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LR33
      Conserved Domains (2) summary
      cd13721
      Location:430 → 724
      PBP2_iGluR_Kainate_GluR6; GluR6 subtype of kainate receptor, type 2 periplasmic-binding fold superfamily
      cd06382
      Location:37 → 414
      PBP1_iGluR_Kainate; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the kainate receptors

    2. XM_059889840.1 → XP_059745823.1  glutamate receptor ionotropic, kainate 2 isoform X3

    3. XM_024996832.2 → XP_024852600.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LR33, A0A3Q1M7Q8
      Related
      ENSBTAP00000066433.2, ENSBTAT00000067226.2
      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    4. XM_024996835.2 → XP_024852603.1  glutamate receptor ionotropic, kainate 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LR33, F1MG21
      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    5. XM_024996833.2 → XP_024852601.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LR33, A0A3Q1M7Q8
      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    6. XM_024996834.2 → XP_024852602.1  glutamate receptor ionotropic, kainate 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LR33, F1MG21
      Related
      ENSBTAP00000015563.6, ENSBTAT00000015563.7
      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    7. XM_024996837.2 → XP_024852605.1  glutamate receptor ionotropic, kainate 2 isoform X5

      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 546
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    8. XM_059889841.1 → XP_059745824.1  glutamate receptor ionotropic, kainate 2 isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version

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