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    ACADL acyl-CoA dehydrogenase long chain [ Bos taurus (domestic cattle) ]

    Gene ID: 614508, updated on 4-Oct-2024

    Summary

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    Official Symbol
    ACADLprovided by VGNC
    Official Full Name
    acyl-CoA dehydrogenase long chainprovided by VGNC
    Primary source
    VGNC:VGNC:25523
    See related
    BGD:BT11286; Ensembl:ENSBTAG00000010579
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ACADL in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (97977177..98029364, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene unc-80 homolog, NALCN channel complex subunit Neighboring gene KAT8 regulatory NSL complex subunit 1 like Neighboring gene ribulose-5-phosphate-3-epimerase Neighboring gene ninjurin-1-like Neighboring gene myosin light chain 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC151674

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables long-chain fatty acyl-CoA dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables palmitoyl-CoA oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carnitine metabolic process, CoA-linked IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in long-chain fatty acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    long-chain specific acyl-CoA dehydrogenase, mitochondrial
    Names
    acyl-Coenzyme A dehydrogenase, long chain
    NP_001070404.1
    XP_024833385.1
    XP_024833388.1
    XP_024833390.1
    XP_024833400.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076936.1 → NP_001070404.1  long-chain specific acyl-CoA dehydrogenase, mitochondrial

      See identical proteins and their annotated locations for NP_001070404.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123880
      UniProtKB/TrEMBL
      F1MN00, Q08D92
      Related
      ENSBTAP00000013988.6, ENSBTAT00000013988.6
      Conserved Domains (2) summary
      cd01160
      Location:56 → 427
      LCAD; Long chain acyl-CoA dehydrogenase
      COG1960
      Location:53 → 430
      CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      97977177..98029364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977620.2 → XP_024833388.1  long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X2

      Conserved Domains (1) summary
      cl09933
      Location:59 → 392
      ACAD; Acyl-CoA dehydrogenase

    2. XM_024977617.2 → XP_024833385.1  long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0AAA9U0U6
      Related
      ENSBTAP00000103305.1, ENSBTAT00000104256.1
      Conserved Domains (1) summary
      cd01160
      Location:59 → 430
      LCAD; Long chain acyl-CoA dehydrogenase

    3. XM_024977632.2 → XP_024833400.1  long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X4

      Conserved Domains (1) summary
      cl09933
      Location:59 → 384
      ACAD; Acyl-CoA dehydrogenase

    4. XM_024977622.2 → XP_024833390.1  long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0AAA9TID5
      Related
      ENSBTAP00000095979.1, ENSBTAT00000103587.1
      Conserved Domains (1) summary
      cl09933
      Location:56 → 389
      ACAD; Acyl-CoA dehydrogenase
    Nucleotide Protein Strain
    Heading Accession and Version

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