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    KRT6A keratin 6A [ Bos taurus (domestic cattle) ]

    Gene ID: 614456, updated on 4-Oct-2024

    Summary

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    Gene symbol
    KRT6A
    Gene description
    keratin 6A
    See related
    BGD:BT11790; Ensembl:ENSBTAG00000040019
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    See KRT6A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (27384552..27389805)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene keratin 71 Neighboring gene keratin 5 Neighboring gene keratin 6B Neighboring gene keratin 6C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes. Blessing M, et al. EMBO J, 1989 Jan. PMID 2469572, Free PMC Article
    2. Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5'-upstream sequences. Blessing M, et al. EMBO J, 1987 Mar. PMID 2438131, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC151786

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural constituent of skin epidermis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intermediate filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in keratinization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in keratin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    keratin, type II cytoskeletal 6A
    Names
    keratin 6 alpha
    keratin IV

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083510.1 → NP_001076979.1  keratin, type II cytoskeletal 6A

      See identical proteins and their annotated locations for NP_001076979.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123886
      UniProtKB/TrEMBL
      A4FV94, F1MKE7
      Related
      ENSBTAP00000060106.2, ENSBTAT00000072211.2
      Conserved Domains (3) summary
      pfam00038
      Location:162 → 475
      Filament; Intermediate filament protein
      pfam16208
      Location:16 → 159
      Keratin_2_head; Keratin type II head
      cl01888
      Location:388 → 448
      DUF883; Bacterial protein of unknown function (DUF883)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      27384552..27389805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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