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    GSTO2 glutathione S-transferase omega 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 613905, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GSTO2provided by VGNC
    Official Full Name
    glutathione S-transferase omega 2provided by VGNC
    Primary source
    VGNC:VGNC:29687
    See related
    BGD:BT26225; Ensembl:ENSBTAG00000040290
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    Location:
    chromosome: 26
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (24836279..24858234)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112444463 Neighboring gene glutathione S-transferase omega-1 Neighboring gene glutathione S-transferase omega 1 Neighboring gene inositol 1,4,5-trisphosphate receptor interacting protein Neighboring gene cilia and flagella associated protein 58

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The developmental origin and compartmentalization of glutathione-s-transferase omega 2 isoforms in the perinuclear theca of eutherian spermatozoa. Hamilton LE, et al. Biol Reprod, 2017 Oct 1. PMID 29036365, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione dehydrogenase (ascorbate) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-ascorbic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione S-transferase omega-2
    NP_001193084.1
    XP_024841559.1
    XP_059737916.1
    XP_059737917.1
    XP_059737918.1
    XP_059737919.1
    XP_059737920.1
    XP_059737921.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206155.2 → NP_001193084.1  glutathione S-transferase omega-2

      See identical proteins and their annotated locations for NP_001193084.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000026
      UniProtKB/TrEMBL
      E1BED9
      Related
      ENSBTAP00000005211.4, ENSBTAT00000005211.4
      Conserved Domains (2) summary
      cd03184
      Location:108 → 230
      GST_C_Omega; C-terminal, alpha helical domain of Class Omega Glutathione S-transferases
      cd03055
      Location:7 → 94
      GST_N_Omega; GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      24836279..24858234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881936.1 → XP_059737919.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9

    2. XM_059881937.1 → XP_059737920.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9

    3. XM_059881933.1 → XP_059737916.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9

    4. XM_024985791.2 → XP_024841559.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9
      Conserved Domains (2) summary
      cd03184
      Location:108 → 230
      GST_C_Omega; C-terminal, alpha helical domain of Class Omega Glutathione S-transferases
      cd03055
      Location:7 → 94
      GST_N_Omega; GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    5. XM_059881938.1 → XP_059737921.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9

    6. XM_059881935.1 → XP_059737918.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9

    7. XM_059881934.1 → XP_059737917.1  glutathione S-transferase omega-2 isoform X1

      UniProtKB/TrEMBL
      E1BED9
    Nucleotide Protein Strain
    Heading Accession and Version

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