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    DCX doublecortin [ Canis lupus familiaris (dog) ]

    Gene ID: 612950, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DCXprovided by VGNC
    Official Full Name
    doublecortinprovided by VGNC
    Primary source
    VGNC:VGNC:54132
    See related
    Ensembl:ENSCAFG00845022487
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See DCX in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (86062412..86202409, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (70501790..70641477, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (85051446..85192159, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (83553159..83685002, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (85222965..85362879, complement)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene p21 (RAC1) activated kinase 3 Neighboring gene U6 spliceosomal RNA Neighboring gene calpain 6 Neighboring gene U4 spliceosomal RNA Neighboring gene transcriptional adapter 3-like Neighboring gene 40S ribosomal protein S27-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of cell adhesion molecules and doublecortin in canine anaplastic meningiomas. Ide T, et al. Vet Pathol, 2011 Jan. PMID 21123860
    2. Immunohistochemical study of doublecortin and nucleostemin in canine brain. De Nevi E, et al. Eur J Histochem, 2013 Mar 20. PMID 23549468, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axoneme assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in photoreceptor cell development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in retina development in camera-type eye IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axoneme IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal migration protein doublecortin
    Names
    doublecortex; lissencephaly, X-linked (doublecortin)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      86062412..86202409 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038450659.1 → XP_038306587.1  neuronal migration protein doublecortin isoform X7

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Related
      ENSCAFP00845031205.1, ENSCAFT00845039844.1
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    2. XM_038450656.1 → XP_038306584.1  neuronal migration protein doublecortin isoform X4

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Related
      ENSCAFP00845031157.1, ENSCAFT00845039781.1
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    3. XM_038450655.1 → XP_038306583.1  neuronal migration protein doublecortin isoform X3

      UniProtKB/TrEMBL
      A0A8I3PPN1, A0A8P0PRE7
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    4. XM_038450658.1 → XP_038306586.1  neuronal migration protein doublecortin isoform X6

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    5. XM_038450654.1 → XP_038306582.1  neuronal migration protein doublecortin isoform X2

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Related
      ENSCAFP00845031109.1, ENSCAFT00845039717.1
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    6. XM_038450653.1 → XP_038306581.1  neuronal migration protein doublecortin isoform X1

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    7. XM_038450660.1 → XP_038306588.1  neuronal migration protein doublecortin isoform X8

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    8. XM_038450657.1 → XP_038306585.1  neuronal migration protein doublecortin isoform X5

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      83553159..83685002 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038524124.1 → XP_038380052.1  neuronal migration protein doublecortin isoform X7

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    2. XM_038524121.1 → XP_038380049.1  neuronal migration protein doublecortin isoform X4

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    3. XM_038524120.1 → XP_038380048.1  neuronal migration protein doublecortin isoform X3

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    4. XM_038524123.1 → XP_038380051.1  neuronal migration protein doublecortin isoform X6

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    5. XM_038524118.1 → XP_038380046.1  neuronal migration protein doublecortin isoform X2

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    6. XM_038524117.1 → XP_038380045.1  neuronal migration protein doublecortin isoform X1

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    7. XM_038524125.1 → XP_038380053.1  neuronal migration protein doublecortin isoform X8

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    8. XM_038524122.1 → XP_038380050.1  neuronal migration protein doublecortin isoform X5

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      85222965..85362879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038652615.1 → XP_038508543.1  neuronal migration protein doublecortin isoform X7

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    2. XM_038652612.1 → XP_038508540.1  neuronal migration protein doublecortin isoform X4

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    3. XM_038652611.1 → XP_038508539.1  neuronal migration protein doublecortin isoform X3

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    4. XM_038652614.1 → XP_038508542.1  neuronal migration protein doublecortin isoform X6

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    5. XM_038652610.1 → XP_038508538.1  neuronal migration protein doublecortin isoform X2

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    6. XM_038652609.1 → XP_038508537.1  neuronal migration protein doublecortin isoform X1

      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    7. XM_038652616.1 → XP_038508544.1  neuronal migration protein doublecortin isoform X8

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    8. XM_038652613.1 → XP_038508541.1  neuronal migration protein doublecortin isoform X5

      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      85051446..85192159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038588099.1 → XP_038444027.1  neuronal migration protein doublecortin isoform X7

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    2. XM_038588096.1 → XP_038444024.1  neuronal migration protein doublecortin isoform X4

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    3. XM_038588095.1 → XP_038444023.1  neuronal migration protein doublecortin isoform X3

      UniProtKB/TrEMBL
      A0A8I3PPN1, A0A8P0PRE7
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    4. XM_038588098.1 → XP_038444026.1  neuronal migration protein doublecortin isoform X6

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    5. XM_038588094.1 → XP_038444022.1  neuronal migration protein doublecortin isoform X2

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    6. XM_038588093.1 → XP_038444021.1  neuronal migration protein doublecortin isoform X1

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    7. XM_038588100.1 → XP_038444028.1  neuronal migration protein doublecortin isoform X8

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    8. XM_038588097.1 → XP_038444025.1  neuronal migration protein doublecortin isoform X5

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      70501790..70641477 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022415823.2 → XP_022271531.1  neuronal migration protein doublecortin isoform X7

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    2. XM_022415820.2 → XP_022271528.1  neuronal migration protein doublecortin isoform X4

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    3. XM_022415819.2 → XP_022271527.1  neuronal migration protein doublecortin isoform X3

      UniProtKB/TrEMBL
      A0A8I3PPN1, A0A8P0PRE7
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 393
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    4. XM_022415821.2 → XP_022271529.1  neuronal migration protein doublecortin isoform X6

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    5. XM_022415818.2 → XP_022271526.1  neuronal migration protein doublecortin isoform X2

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    6. XM_022415817.2 → XP_022271525.1  neuronal migration protein doublecortin isoform X1

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (3) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
      cl40450
      Location:339 → 398
      KLF8_12_N; N-terminal domain of Kruppel-like factor (KLF) 8, KLF12, and similar proteins

    7. XM_022415824.2 → XP_022271532.1  neuronal migration protein doublecortin isoform X8

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2

    8. XM_022415822.2 → XP_022271530.1  neuronal migration protein doublecortin isoform X5

      UniProtKB/TrEMBL
      A0A8C0JYM9
      Conserved Domains (2) summary
      cd16112
      Location:106 → 194
      DCX1_DCX; Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX)
      cd17069
      Location:231 → 314
      DCX2; Dublecortin-like domain 2
    Nucleotide Protein
    Heading Accession and Version

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