U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    NR1H2 nuclear receptor subfamily 1 group H member 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 610057, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NR1H2provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group H member 2provided by VGNC
    Primary source
    VGNC:VGNC:43942
    See related
    Ensembl:ENSCAFG00845018363
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NR1H2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (106843783..106850258, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (105905786..105912261, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (106998070..107004546, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (106515887..106522355, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (106157420..106163895, complement)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene Spi-B transcription factor Neighboring gene DNA polymerase delta 1, catalytic subunit Neighboring gene napsin A aspartic peptidase Neighboring gene uncharacterized LOC119870938 Neighboring gene potassium voltage-gated channel subfamily C member 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    oxysterols receptor LXR-beta

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      106843783..106850258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038656192.1 → XP_038512120.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. XM_038656190.1 → XP_038512118.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    3. XM_038656191.1 → XP_038512119.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Related
      ENSCAFP00845025424.1, ENSCAFT00845032512.1
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      106515887..106522355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038467405.1 → XP_038323333.1  oxysterols receptor LXR-beta

      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. XM_038467403.1 → XP_038323331.1  oxysterols receptor LXR-beta

      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    3. XM_038467404.1 → XP_038323332.1  oxysterols receptor LXR-beta

      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      106157420..106163895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038592400.1 → XP_038448328.1  oxysterols receptor LXR-beta

      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. XM_038592398.1 → XP_038448326.1  oxysterols receptor LXR-beta

      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    3. XM_038592399.1 → XP_038448327.1  oxysterols receptor LXR-beta

      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      106998070..107004546 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038528103.1 → XP_038384031.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. XM_038528101.1 → XP_038384029.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    3. XM_038528102.1 → XP_038384030.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      105905786..105912261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022423354.2 → XP_022279062.1  oxysterols receptor LXR-beta

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. XM_005616270.4 → XP_005616327.1  oxysterols receptor LXR-beta

      See identical proteins and their annotated locations for XP_005616327.1

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    3. XM_846223.6 → XP_851316.1  oxysterols receptor LXR-beta

      See identical proteins and their annotated locations for XP_851316.1

      UniProtKB/TrEMBL
      A0A8C0L554, A0A8C0SEE4, A0A8I3NW80
      Conserved Domains (2) summary
      cd06954
      Location:218 → 453
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:65 → 161
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.