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    POFUT1 protein O-fucosyltransferase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 609881, updated on 17-Aug-2024

    Summary

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    Official Symbol
    POFUT1provided by VGNC
    Official Full Name
    protein O-fucosyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:44767
    See related
    Ensembl:ENSCAFG00845020869
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See POFUT1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (22295373..22325022)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (21255008..21280646)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (22110055..22136141)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (21573904..21599988)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (21679257..21705352)

    Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene uncharacterized LOC111092032 Neighboring gene PLAG1 like zinc finger 2 Neighboring gene uncharacterized LOC111092036 Neighboring gene kinesin family member 3B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of protein O-fucosyltransferase genes and splice variants. Loriol C, et al. Glycobiology, 2006 Aug. PMID 16679357
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptide-O-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein O-linked fucosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDP-fucose protein O-fucosyltransferase 1
    NP_001070825.1
    XP_038288768.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077357.1 → NP_001070825.1  GDP-fucose protein O-fucosyltransferase 1 precursor

      See identical proteins and their annotated locations for NP_001070825.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ139940
      UniProtKB/TrEMBL
      A0A8P0SCM8, Q00P48
      Related
      ENSCAFP00845028826.1, ENSCAFT00845036817.1
      Conserved Domains (2) summary
      cd11302
      Location:33 → 382
      O-FucT-1; GDP-fucose protein O-fucosyltransferase 1
      pfam10250
      Location:43 → 374
      O-FucT; GDP-fucose protein O-fucosyltransferase

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051828.1 Reference ROS_Cfam_1.0

      Range
      22295373..22325022
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038432840.1 → XP_038288768.1  GDP-fucose protein O-fucosyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8P0SCM8
      Conserved Domains (1) summary
      cd11302
      Location:15 → 356
      O-FucT-1; GDP-fucose protein O-fucosyltransferase 1

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049284.1 Alternate UMICH_Zoey_3.1

      Range
      21573904..21599988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

      Range
      21679257..21705352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

      Range
      22110055..22136141
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      21255008..21280646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials