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    ATP6V0A1 ATPase H+ transporting V0 subunit a1 [ Canis lupus familiaris (dog) ]

    Gene ID: 607705, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ATP6V0A1provided by VGNC
    Official Full Name
    ATPase H+ transporting V0 subunit a1provided by VGNC
    Primary source
    VGNC:VGNC:38268
    See related
    Ensembl:ENSCAFG00845008916
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ATP6V0A1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (21141094..21205623, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (19883979..19948472, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (20296209..20360734, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (19926898..19991407, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (20192140..20256660, complement)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene hydroxysteroid 17-beta dehydrogenase 1 Neighboring gene N-acetyl-alpha-glucosaminidase Neighboring gene caveolae associated protein 1 Neighboring gene signal transducer and activator of transcription 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables proton-transporting ATPase activity, rotational mechanism IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vacuolar acidification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of vacuolar proton-transporting V-type ATPase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of vacuolar proton-transporting V-type ATPase, V0 domain IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    V-type proton ATPase 116 kDa subunit a isoform 1; V-type proton ATPase 116 kDa subunit a1
    XP_013972025.1
    XP_013972026.1
    XP_013972027.1
    XP_013972028.1
    XP_013972030.1
    XP_013972032.1
    XP_038341438.1
    XP_038341439.1
    XP_038341440.1
    XP_038341441.1
    XP_038341442.1
    XP_038341443.1
    XP_038341444.1
    XP_038341445.1
    XP_038341446.1
    XP_038403202.1
    XP_038403203.1
    XP_038403204.1
    XP_038403205.1
    XP_038403206.1
    XP_038403207.1
    XP_038403208.1
    XP_038403209.1
    XP_038403210.1
    XP_038467172.1
    XP_038467173.1
    XP_038467174.1
    XP_038467175.1
    XP_038467176.1
    XP_038467177.1
    XP_038467178.1
    XP_038467179.1
    XP_038467180.1
    XP_038532360.1
    XP_038532361.1
    XP_038532362.1
    XP_038532363.1
    XP_038532364.1
    XP_038532365.1
    XP_038532366.1
    XP_038532367.1
    XP_038532368.1
    XP_849622.2
    XP_859219.1
    XP_859260.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      21141094..21205623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038676439.1 → XP_038532367.1  V-type proton ATPase 116 kDa subunit a1 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LSR5, A0A8I3NLM3, A0A8P0NGI3
      Related
      ENSCAFP00845012186.1, ENSCAFT00845015670.1
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 822
      V_ATPase_I; V-type ATPase 116kDa subunit family

    2. XM_038676438.1 → XP_038532366.1  V-type proton ATPase 116 kDa subunit a1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 828
      V_ATPase_I; V-type ATPase 116kDa subunit family

    3. XM_038676435.1 → XP_038532363.1  V-type proton ATPase 116 kDa subunit a1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LSR5, A0A8C0S097, A0A8I3RWI5
      Related
      ENSCAFP00845012406.1, ENSCAFT00845015944.1
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 853
      V_ATPase_I; V-type ATPase 116kDa subunit family

    4. XM_038676437.1 → XP_038532365.1  V-type proton ATPase 116 kDa subunit a1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KHH5, A0A8C0LSR5, A0A8C0LW48
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 829
      V_ATPase_I; V-type ATPase 116kDa subunit family

    5. XM_038676436.1 → XP_038532364.1  V-type proton ATPase 116 kDa subunit a1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 835
      V_ATPase_I; V-type ATPase 116kDa subunit family

    6. XM_038676434.1 → XP_038532362.1  V-type proton ATPase 116 kDa subunit a1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 854
      V_ATPase_I; V-type ATPase 116kDa subunit family

    7. XM_038676432.1 → XP_038532360.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    8. XM_038676433.1 → XP_038532361.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Related
      ENSCAFP00845012492.1, ENSCAFT00845016065.1
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    9. XM_038676440.1 → XP_038532368.1  V-type proton ATPase 116 kDa subunit a1 isoform X8

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:2 → 781
      V_ATPase_I; V-type ATPase 116kDa subunit family

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      19926898..19991407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038485517.1 → XP_038341445.1  V-type proton ATPase 116 kDa subunit a1 isoform X7

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 822
      V_ATPase_I; V-type ATPase 116kDa subunit family

    2. XM_038485516.1 → XP_038341444.1  V-type proton ATPase 116 kDa subunit a1 isoform X6

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 828
      V_ATPase_I; V-type ATPase 116kDa subunit family

    3. XM_038485513.1 → XP_038341441.1  V-type proton ATPase 116 kDa subunit a1 isoform X3

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 853
      V_ATPase_I; V-type ATPase 116kDa subunit family

    4. XM_038485515.1 → XP_038341443.1  V-type proton ATPase 116 kDa subunit a1 isoform X5

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 829
      V_ATPase_I; V-type ATPase 116kDa subunit family

    5. XM_038485514.1 → XP_038341442.1  V-type proton ATPase 116 kDa subunit a1 isoform X4

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 835
      V_ATPase_I; V-type ATPase 116kDa subunit family

    6. XM_038485512.1 → XP_038341440.1  V-type proton ATPase 116 kDa subunit a1 isoform X2

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 854
      V_ATPase_I; V-type ATPase 116kDa subunit family

    7. XM_038485510.1 → XP_038341438.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    8. XM_038485511.1 → XP_038341439.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    9. XM_038485518.1 → XP_038341446.1  V-type proton ATPase 116 kDa subunit a1 isoform X8

      Conserved Domains (1) summary
      pfam01496
      Location:2 → 781
      V_ATPase_I; V-type ATPase 116kDa subunit family

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      20192140..20256660 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038611251.1 → XP_038467179.1  V-type proton ATPase 116 kDa subunit a1 isoform X7

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 822
      V_ATPase_I; V-type ATPase 116kDa subunit family

    2. XM_038611250.1 → XP_038467178.1  V-type proton ATPase 116 kDa subunit a1 isoform X6

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 828
      V_ATPase_I; V-type ATPase 116kDa subunit family

    3. XM_038611247.1 → XP_038467175.1  V-type proton ATPase 116 kDa subunit a1 isoform X3

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 853
      V_ATPase_I; V-type ATPase 116kDa subunit family

    4. XM_038611249.1 → XP_038467177.1  V-type proton ATPase 116 kDa subunit a1 isoform X5

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 829
      V_ATPase_I; V-type ATPase 116kDa subunit family

    5. XM_038611248.1 → XP_038467176.1  V-type proton ATPase 116 kDa subunit a1 isoform X4

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 835
      V_ATPase_I; V-type ATPase 116kDa subunit family

    6. XM_038611246.1 → XP_038467174.1  V-type proton ATPase 116 kDa subunit a1 isoform X2

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 854
      V_ATPase_I; V-type ATPase 116kDa subunit family

    7. XM_038611244.1 → XP_038467172.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    8. XM_038611245.1 → XP_038467173.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    9. XM_038611252.1 → XP_038467180.1  V-type proton ATPase 116 kDa subunit a1 isoform X8

      Conserved Domains (1) summary
      pfam01496
      Location:2 → 781
      V_ATPase_I; V-type ATPase 116kDa subunit family

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      20296209..20360734 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038547281.1 → XP_038403209.1  V-type proton ATPase 116 kDa subunit a1 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LSR5, A0A8I3NLM3, A0A8P0NGI3
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 822
      V_ATPase_I; V-type ATPase 116kDa subunit family

    2. XM_038547280.1 → XP_038403208.1  V-type proton ATPase 116 kDa subunit a1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 828
      V_ATPase_I; V-type ATPase 116kDa subunit family

    3. XM_038547277.1 → XP_038403205.1  V-type proton ATPase 116 kDa subunit a1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LSR5, A0A8C0S097, A0A8I3RWI5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 853
      V_ATPase_I; V-type ATPase 116kDa subunit family

    4. XM_038547279.1 → XP_038403207.1  V-type proton ATPase 116 kDa subunit a1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KHH5, A0A8C0LSR5, A0A8C0LW48
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 829
      V_ATPase_I; V-type ATPase 116kDa subunit family

    5. XM_038547278.1 → XP_038403206.1  V-type proton ATPase 116 kDa subunit a1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 835
      V_ATPase_I; V-type ATPase 116kDa subunit family

    6. XM_038547276.1 → XP_038403204.1  V-type proton ATPase 116 kDa subunit a1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 854
      V_ATPase_I; V-type ATPase 116kDa subunit family

    7. XM_038547274.1 → XP_038403202.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    8. XM_038547275.1 → XP_038403203.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    9. XM_038547282.1 → XP_038403210.1  V-type proton ATPase 116 kDa subunit a1 isoform X8

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:2 → 781
      V_ATPase_I; V-type ATPase 116kDa subunit family

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      19883979..19948472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_854167.5 → XP_859260.1  V-type proton ATPase 116 kDa subunit a1 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LSR5, A0A8I3NLM3, A0A8P0NGI3
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 822
      V_ATPase_I; V-type ATPase 116kDa subunit family

    2. XM_844529.5 → XP_849622.2  V-type proton ATPase 116 kDa subunit a1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 828
      V_ATPase_I; V-type ATPase 116kDa subunit family

    3. XM_014116553.2 → XP_013972028.1  V-type proton ATPase 116 kDa subunit a1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LSR5, A0A8C0S097, A0A8I3RWI5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 853
      V_ATPase_I; V-type ATPase 116kDa subunit family

    4. XM_854126.5 → XP_859219.1  V-type proton ATPase 116 kDa subunit a1 isoform X5

      See identical proteins and their annotated locations for XP_859219.1

      UniProtKB/TrEMBL
      A0A8C0KHH5, A0A8C0LSR5, A0A8C0LW48
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 829
      V_ATPase_I; V-type ATPase 116kDa subunit family

    5. XM_014116555.2 → XP_013972030.1  V-type proton ATPase 116 kDa subunit a1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 835
      V_ATPase_I; V-type ATPase 116kDa subunit family

    6. XM_014116552.2 → XP_013972027.1  V-type proton ATPase 116 kDa subunit a1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 854
      V_ATPase_I; V-type ATPase 116kDa subunit family

    7. XM_014116550.2 → XP_013972025.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    8. XM_014116551.3 → XP_013972026.1  V-type proton ATPase 116 kDa subunit a1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:27 → 860
      V_ATPase_I; V-type ATPase 116kDa subunit family

    9. XM_014116557.3 → XP_013972032.1  V-type proton ATPase 116 kDa subunit a1 isoform X8

      UniProtKB/TrEMBL
      A0A8C0LSR5
      Conserved Domains (1) summary
      pfam01496
      Location:2 → 781
      V_ATPase_I; V-type ATPase 116kDa subunit family
    Nucleotide Protein
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