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    METTL1 methyltransferase 1, tRNA methylguanosine [ Canis lupus familiaris (dog) ]

    Gene ID: 607590, updated on 17-Aug-2024

    Summary

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    Official Symbol
    METTL1provided by VGNC
    Official Full Name
    methyltransferase 1, tRNA methylguanosineprovided by VGNC
    Primary source
    VGNC:VGNC:43169
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See METTL1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (1840276..1843693, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (1894060..1897477, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (2184948..2188346, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (1817972..1821388, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (2060022..2063439, complement)

    Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 9 Neighboring gene cytochrome P450 family 27 subfamily B member 1 Neighboring gene EEF1A lysine methyltransferase 3 Neighboring gene Ts translation elongation factor, mitochondrial

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tRNA (guanine(46)-N7)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA (guanine-N7)-methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of tRNA methyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA (guanine-N(7)-)-methyltransferase
    Names
    methyltransferase like 1
    XP_038343864.1
    XP_038343865.1
    XP_038343866.1
    XP_038343867.1
    XP_038343868.1
    XP_038405757.1
    XP_038405758.1
    XP_038405759.1
    XP_038405760.1
    XP_038405761.1
    XP_038469724.1
    XP_038469725.1
    XP_038469726.1
    XP_038469727.1
    XP_038469728.1
    XP_038489606.1
    XP_038489615.1
    XP_038489618.1
    XP_038489626.1
    XP_038489635.1
    XP_038535079.1
    XP_038535080.1
    XP_038535081.1
    XP_038535082.1
    XP_038535083.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051814.1 Reference ROS_Cfam_1.0

      Range
      1840276..1843693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038679153.1 → XP_038535081.1  tRNA (guanine-N(7)-)-methyltransferase isoform X3

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 251
      Methyltransf_4; Putative methyltransferase

    2. XM_038679154.1 → XP_038535082.1  tRNA (guanine-N(7)-)-methyltransferase isoform X4

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    3. XM_038679151.1 → XP_038535079.1  tRNA (guanine-N(7)-)-methyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A8C0T000
      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    4. XM_038679155.1 → XP_038535083.1  tRNA (guanine-N(7)-)-methyltransferase isoform X5

      Conserved Domains (1) summary
      pfam02390
      Location:34 → 211
      Methyltransf_4; Putative methyltransferase

    5. XM_038679152.1 → XP_038535080.1  tRNA (guanine-N(7)-)-methyltransferase isoform X2

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 253
      Methyltransf_4; Putative methyltransferase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049270.1 Alternate UMICH_Zoey_3.1

      Range
      1817972..1821388 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038487938.1 → XP_038343866.1  tRNA (guanine-N(7)-)-methyltransferase isoform X3

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 251
      Methyltransf_4; Putative methyltransferase

    2. XM_038487939.1 → XP_038343867.1  tRNA (guanine-N(7)-)-methyltransferase isoform X4

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    3. XM_038487936.1 → XP_038343864.1  tRNA (guanine-N(7)-)-methyltransferase isoform X1

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    4. XM_038487940.1 → XP_038343868.1  tRNA (guanine-N(7)-)-methyltransferase isoform X5

      Conserved Domains (1) summary
      pfam02390
      Location:34 → 211
      Methyltransf_4; Putative methyltransferase

    5. XM_038487937.1 → XP_038343865.1  tRNA (guanine-N(7)-)-methyltransferase isoform X2

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 253
      Methyltransf_4; Putative methyltransferase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

      Range
      2060022..2063439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038613798.1 → XP_038469726.1  tRNA (guanine-N(7)-)-methyltransferase isoform X3

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 251
      Methyltransf_4; Putative methyltransferase

    2. XM_038613799.1 → XP_038469727.1  tRNA (guanine-N(7)-)-methyltransferase isoform X4

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    3. XM_038613796.1 → XP_038469724.1  tRNA (guanine-N(7)-)-methyltransferase isoform X1

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    4. XM_038613800.1 → XP_038469728.1  tRNA (guanine-N(7)-)-methyltransferase isoform X5

      Conserved Domains (1) summary
      pfam02390
      Location:34 → 211
      Methyltransf_4; Putative methyltransferase

    5. XM_038613797.1 → XP_038469725.1  tRNA (guanine-N(7)-)-methyltransferase isoform X2

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 253
      Methyltransf_4; Putative methyltransferase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

      Range
      2184948..2188346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038549831.1 → XP_038405759.1  tRNA (guanine-N(7)-)-methyltransferase isoform X3

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 251
      Methyltransf_4; Putative methyltransferase

    2. XM_038549832.1 → XP_038405760.1  tRNA (guanine-N(7)-)-methyltransferase isoform X4

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    3. XM_038549829.1 → XP_038405757.1  tRNA (guanine-N(7)-)-methyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A8C0T000
      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    4. XM_038549833.1 → XP_038405761.1  tRNA (guanine-N(7)-)-methyltransferase isoform X5

      Conserved Domains (1) summary
      pfam02390
      Location:34 → 211
      Methyltransf_4; Putative methyltransferase

    5. XM_038549830.1 → XP_038405758.1  tRNA (guanine-N(7)-)-methyltransferase isoform X2

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 253
      Methyltransf_4; Putative methyltransferase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      1894060..1897477 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038633690.1 → XP_038489618.1  tRNA (guanine-N(7)-)-methyltransferase isoform X3

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 251
      Methyltransf_4; Putative methyltransferase

    2. XM_038633698.1 → XP_038489626.1  tRNA (guanine-N(7)-)-methyltransferase isoform X4

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    3. XM_038633678.1 → XP_038489606.1  tRNA (guanine-N(7)-)-methyltransferase isoform X1

      UniProtKB/TrEMBL
      A0A8C0T000
      Conserved Domains (1) summary
      pfam02390
      Location:82 → 259
      Methyltransf_4; Putative methyltransferase

    4. XM_038633707.1 → XP_038489635.1  tRNA (guanine-N(7)-)-methyltransferase isoform X5

      Conserved Domains (1) summary
      pfam02390
      Location:34 → 211
      Methyltransf_4; Putative methyltransferase

    5. XM_038633687.1 → XP_038489615.1  tRNA (guanine-N(7)-)-methyltransferase isoform X2

      Conserved Domains (1) summary
      pfam02390
      Location:82 → 253
      Methyltransf_4; Putative methyltransferase
    Nucleotide Protein
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