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    zdhhc14 zinc finger DHHC-type palmitoyltransferase 14 [ Danio rerio (zebrafish) ]

    Gene ID: 569667, updated on 18-Sep-2024

    Summary

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    Official Symbol
    zdhhc14provided by ZNC
    Official Full Name
    zinc finger DHHC-type palmitoyltransferase 14provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040724-21
    See related
    Ensembl:ENSDARG00000037069 AllianceGenome:ZFIN:ZDB-GENE-040724-21
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    DHHC-14; si:ch211-199l3.1
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC14 (zinc finger DHHC-type palmitoyltransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See zdhhc14 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (4827742..4884407, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (4784812..4841722, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene galactosylceramidase a Neighboring gene galectin 8a Neighboring gene transmembrane protein 242 Neighboring gene AT-rich interactive domain 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 2-Bromopalmitate impairs neural stem/progenitor cell proliferation, promotes cell apoptosis and induces malformation in zebrafish embryonic brain. Wang C, et al. Neurotoxicol Teratol, 2015 Jul-Aug. PMID 26056731
    2. Galectins in channel catfish, Ictalurus punctatus: Characterization and expression profiling in mucosal tissues. Zhou S, et al. Fish Shellfish Immunol, 2016 Feb. PMID 26767746
    3. Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. Liu Z, et al. J Biol Chem, 2011 Aug 12. PMID 21669877, Free PMC Article
    4. Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Du Z, et al. Biochem Biophys Res Commun, 2016 Jun 24. PMID 27235108
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    palmitoyltransferase ZDHHC14
    Names
    DHHC domain-containing cysteine-rich protein 14
    probable palmitoyltransferase ZDHHC14
    zinc finger DHHC domain-containing protein 14
    zinc finger DHHC-type containing 14
    NP_001038652.1
    XP_005160408.1
    XP_005160409.1
    XP_068071648.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045187.1 → NP_001038652.1  palmitoyltransferase ZDHHC14

      Status: PROVISIONAL

      Source sequence(s)
      AL953887
      UniProtKB/Swiss-Prot
      E9QCD3
      UniProtKB/TrEMBL
      A0A8M1NA34
      Related
      ENSDARP00000114751.2, ENSDART00000145540.4
      Conserved Domains (1) summary
      pfam01529
      Location:163 → 306
      zf-DHHC; DHHC palmitoyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      4827742..4884407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160352.5 → XP_005160409.1  palmitoyltransferase ZDHHC14 isoform X2

      UniProtKB/Swiss-Prot
      E9QCD3
      UniProtKB/TrEMBL
      A0A8M2B765
      Conserved Domains (1) summary
      pfam01529
      Location:163 → 286
      zf-DHHC; DHHC palmitoyltransferase

    2. XM_005160351.5 → XP_005160408.1  palmitoyltransferase ZDHHC14 isoform X1

      UniProtKB/Swiss-Prot
      E9QCD3
      UniProtKB/TrEMBL
      A0A8M2B7H9
      Conserved Domains (1) summary
      pfam01529
      Location:163 → 286
      zf-DHHC; DHHC palmitoyltransferase

    3. XM_068215547.1 → XP_068071648.1  palmitoyltransferase ZDHHC14 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E9QCD3.3 GenPept UniProtKB/Swiss-Prot:E9QCD3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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