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    PAX6 paired box 6 [ Ovis aries (sheep) ]

    Gene ID: 554264, updated on 5-Mar-2024

    Summary

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    Gene symbol
    PAX6
    Gene description
    paired box 6
    See related
    EnsemblRapid:ENSOARG00020007805
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See PAX6 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 15 NC_056068.1 (61376861..61394874, complement)

    Chromosome 15 - NC_056068.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C24 Neighboring gene inner mitochondrial membrane peptidase subunit 1 Neighboring gene elongator acetyltransferase complex subunit 4 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene uncharacterized LOC132657829

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056068.1 Chromosome 15 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    paired box protein Pax-6
    Names
    paired box gene 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056068.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      61376861..61394874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012096165.5 → XP_011951555.1  paired box protein Pax-6 isoform X4

      See identical proteins and their annotated locations for XP_011951555.1

      Conserved Domains (2) summary
      pfam00046
      Location:147 → 200
      Homeobox; Homeobox domain
      cl21459
      Location:4 → 56
      HTH; Helix-turn-helix domains

    2. XM_012096163.5 → XP_011951553.1  paired box protein Pax-6 isoform X2

      See identical proteins and their annotated locations for XP_011951553.1

      UniProtKB/TrEMBL
      A0A6P3T0X5, Q58IJ3, W5Q3U9
      Related
      ENSOARP00020009890.1, ENSOART00020012008.2
      Conserved Domains (2) summary
      smart00351
      Location:4 → 128
      PAX; Paired Box domain
      pfam00046
      Location:214 → 267
      Homeobox; Homeobox domain

    3. XM_012096164.5 → XP_011951554.1  paired box protein Pax-6 isoform X3

      See identical proteins and their annotated locations for XP_011951554.1

      Conserved Domains (2) summary
      pfam00046
      Location:161 → 214
      Homeobox; Homeobox domain
      cl21459
      Location:4 → 70
      HTH; Helix-turn-helix domains

    4. XM_012096162.4 → XP_011951552.1  paired box protein Pax-6 isoform X1

      See identical proteins and their annotated locations for XP_011951552.1

      UniProtKB/TrEMBL
      A0A6P3T9I4, W5Q3U7
      Related
      ENSOARP00020009863.1, ENSOART00020011975.2
      Conserved Domains (2) summary
      smart00351
      Location:4 → 142
      PAX; Paired Box domain
      pfam00046
      Location:228 → 281
      Homeobox; Homeobox domain
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials