ak5l adenylate kinase 5, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ak5lprovided by ZNC
Official Full Name: adenylate kinase 5, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050410-2
See related: Ensembl:ENSDARG00000017739 AllianceGenome:ZFIN:ZDB-GENE-050410-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:113368
Summary: Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in nucleoside diphosphate phosphorylation and nucleoside triphosphate biosynthetic process. Predicted to act upstream of or within nucleobase-containing compound metabolic process and phosphorylation. Predicted to be active in cytosol. Is expressed in diencephalon; pancreas primordium; tegmentum; and telencephalon. Orthologous to human AK5 (adenylate kinase 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (64177502..64203101, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (63496303..63521902, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables adenylate kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleobase-containing compound kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within nucleobase-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: adenylate kinase 5, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017540.2 → NP_001017540.1 adenylate kinase 5, like

See identical proteins and their annotated locations for NP_001017540.1

Status: PROVISIONAL

Source sequence(s)

BC092184

UniProtKB/TrEMBL

A0A8M1N4V3, Q56A38

Related

ENSDARP00000032337.5, ENSDART00000029364.6

Conserved Domains (2) summary

TIGR01360
Location:136 → 314

aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

cd01428
Location:136 → 310

ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...