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    DEK DEK proto-oncogene [ Bos taurus (domestic cattle) ]

    Gene ID: 540945, updated on 4-Oct-2024

    Summary

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    Official Symbol
    DEKprovided by VGNC
    Official Full Name
    DEK proto-oncogeneprovided by VGNC
    Primary source
    VGNC:VGNC:27992
    See related
    Ensembl:ENSBTAG00000012865
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See DEK in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (39355713..39387660)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 144B Neighboring gene uncharacterized LOC112443866 Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene lysine demethylase 1B Neighboring gene thiopurine S-methyltransferase Neighboring gene NHL repeat containing E3 ubiquitin protein ligase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein DEK
    Names
    DEK oncogene (DNA binding)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099717.1 → NP_001093187.1  protein DEK

      See identical proteins and their annotated locations for NP_001093187.1

      Status: PROVISIONAL

      Source sequence(s)
      BC142198
      UniProtKB/TrEMBL
      A0AAA9TCH1, A5PJQ1, F1MCP2
      Related
      ENSBTAP00000017097.5, ENSBTAT00000017097.6
      Conserved Domains (2) summary
      smart00513
      Location:149 → 183
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam08766
      Location:320 → 374
      DEK_C; DEK C terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      39355713..39387660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024983697.2 → XP_024839465.1  protein DEK isoform X1

      UniProtKB/TrEMBL
      A0AAA9TCH1, A5PJQ1, F1MCP2
      Conserved Domains (2) summary
      smart00513
      Location:149 → 183
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam08766
      Location:320 → 374
      DEK_C; DEK C terminal domain

    2. XM_059880421.1 → XP_059736404.1  protein DEK isoform X3

    3. XM_010818493.4 → XP_010816795.1  protein DEK isoform X2

      See identical proteins and their annotated locations for XP_010816795.1

      UniProtKB/TrEMBL
      A0AAA9SKP0
      Related
      ENSBTAP00000086910.1, ENSBTAT00000132619.1
      Conserved Domains (1) summary
      smart00513
      Location:149 → 183
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

    4. XM_010818492.4 → XP_010816794.1  protein DEK isoform X1

      See identical proteins and their annotated locations for XP_010816794.1

      UniProtKB/TrEMBL
      A0AAA9TCH1, A5PJQ1, F1MCP2
      Conserved Domains (2) summary
      smart00513
      Location:149 → 183
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam08766
      Location:320 → 374
      DEK_C; DEK C terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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