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    CBX3 chromobox 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 539788, updated on 4-Oct-2024

    Summary

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    Official Symbol
    CBX3provided by VGNC
    Official Full Name
    chromobox 3provided by VGNC
    Primary source
    VGNC:VGNC:50017
    See related
    Ensembl:ENSBTAG00000049437
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CBX3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (69722996..69734069, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345115 Neighboring gene sorting nexin 10 Neighboring gene uncharacterized LOC107132414 Neighboring gene heterogeneous nuclear ribonucleoprotein A2/B1 Neighboring gene NFE2 like bZIP transcription factor 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamic changes in localization of Chromobox (Cbx) family members during the maternal to embryonic transition. Ruddock-D'Cruz NT, et al. Mol Reprod Dev, 2008 Mar. PMID 17486619
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dynamic changes of the nuclear-cytoplasmic and subnuclear distribution of members of the Cbx family may be central to the maternal to embryonic transition.
      Title: Dynamic changes in localization of Chromobox (Cbx) family members during the maternal to embryonic transition.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of pericentric heterochromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chromobox protein homolog 3
    Names
    chromobox homolog 3 (HP1 gamma homolog, Drosophila)
    chromobox-like protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101198.1 → NP_001094668.1  chromobox protein homolog 3

      See identical proteins and their annotated locations for NP_001094668.1

      Status: PROVISIONAL

      Source sequence(s)
      BC146194
      UniProtKB/TrEMBL
      A6H7C4, F1N1S3
      Related
      ENSBTAP00000058321.1, ENSBTAT00000076903.1
      Conserved Domains (2) summary
      cd18652
      Location:29 → 78
      CD_HP1gamma_Cbx3; chromodomain of heterochromatin protein 1 homolog gamma
      cd18656
      Location:116 → 173
      CSD_HP1gamma_Cbx3; chromo shadow domain of heterochromatin protein 1 gamma homolog gamma

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      69722996..69734069 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990834.2 → XP_024846602.1  chromobox protein homolog 3 isoform X1

      UniProtKB/TrEMBL
      A6H7C4, F1N1S3
      Conserved Domains (2) summary
      cd18652
      Location:29 → 78
      CD_HP1gamma_Cbx3; chromodomain of heterochromatin protein 1 homolog gamma
      cd18656
      Location:116 → 173
      CSD_HP1gamma_Cbx3; chromo shadow domain of heterochromatin protein 1 gamma homolog gamma
    Nucleotide Protein Strain
    Heading Accession and Version

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