U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SPRY2 sprouty RTK signaling antagonist 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 539090, updated on 4-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SPRY2provided by VGNC
    Official Full Name
    sprouty RTK signaling antagonist 2provided by VGNC
    Primary source
    VGNC:VGNC:35242
    See related
    BGD:BT18694; Ensembl:ENSBTAG00000001774
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SPRY2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (55341979..55347266, complement)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene phosphoglycerate mutase 1-like Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Differential display and suppressive subtractive hybridization used to identify granulosa cell messenger rna associated with bovine oocyte developmental competence. Robert C, et al. Biol Reprod, 2001 Jun. PMID 11369613
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC139477

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of fibroblast growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein sprouty homolog 2
    Names
    sprouty homolog 2
    spry-2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076147.1 → NP_001069615.1  protein sprouty homolog 2

      See identical proteins and their annotated locations for NP_001069615.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123435
      UniProtKB/Swiss-Prot
      Q08E39
      UniProtKB/TrEMBL
      A0AAA9SRX0
      Conserved Domains (1) summary
      pfam05210
      Location:183 → 284
      Sprouty; Sprouty protein (Spry)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      55341979..55347266 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005213881.5 → XP_005213938.1  protein sprouty homolog 2 isoform X1

      See identical proteins and their annotated locations for XP_005213938.1

      UniProtKB/Swiss-Prot
      Q08E39
      UniProtKB/TrEMBL
      A0AAA9SRX0
      Related
      ENSBTAP00000095855.1, ENSBTAT00000120651.1
      Conserved Domains (1) summary
      pfam05210
      Location:183 → 284
      Sprouty; Sprouty protein (Spry)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08E39.1 GenPept UniProtKB/Swiss-Prot:Q08E39

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.