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    KCNJ12 potassium inwardly rectifying channel subfamily J member 12 [ Bos taurus (domestic cattle) ]

    Gene ID: 538479, updated on 18-Aug-2024

    Summary

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    Gene symbol
    KCNJ12
    Gene description
    potassium inwardly rectifying channel subfamily J member 12
    See related
    Ensembl:ENSBTAG00000020061
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    IRK2; KIR2.2
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 19
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (35328104..35365897)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase domain containing 1 Neighboring gene mitogen-activated protein kinase kinase 3 Neighboring gene uncharacterized LOC132343055 Neighboring gene spindle and kinetochore-associated protein 3-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distribution and association study in copy number variation of KCNJ12 gene across four Chinese cattle populations. Zheng L, et al. Gene, 2019 Mar 20. PMID 30572095
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inward rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-sensitive inward rectifier potassium channel 12
    Names
    potassium channel, inwardly rectifying subfamily J member 12
    potassium inwardly-rectifying channel J12
    potassium voltage-gated channel subfamily J member 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024690.2 → NP_001019861.2  ATP-sensitive inward rectifier potassium channel 12

      See identical proteins and their annotated locations for NP_001019861.2

      Status: PROVISIONAL

      Source sequence(s)
      BC133380
      UniProtKB/TrEMBL
      A2VDS5
      Related
      ENSBTAP00000077541.1, ENSBTAT00000119931.1
      Conserved Domains (2) summary
      pfam01007
      Location:47 → 374
      IRK; Inward rectifier potassium channel
      pfam08466
      Location:3 → 46
      IRK_N; Inward rectifier potassium channel N-terminal

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35328104..35365897
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220595.5 → XP_005220652.2  ATP-sensitive inward rectifier potassium channel 12 isoform X1

      UniProtKB/Swiss-Prot
      Q4TZY1
      Related
      ENSBTAP00000086488.1, ENSBTAT00000114144.1
      Conserved Domains (3) summary
      pfam01007
      Location:47 → 187
      IRK; Inward rectifier potassium channel
      pfam08466
      Location:2 → 46
      IRK_N; Inward rectifier potassium channel N-terminal
      pfam17655
      Location:194 → 366
      IRK_C; Inward rectifier potassium channel C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4TZY1.1 GenPept UniProtKB/Swiss-Prot:Q4TZY1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.