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    SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 537503, updated on 4-Oct-2024

    Summary

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    Official Symbol
    SMARCA5provided by VGNC
    Official Full Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5provided by VGNC
    Primary source
    VGNC:VGNC:34988
    See related
    BGD:BT17345; Ensembl:ENSBTAG00000003399
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SMARCA5 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (14342538..14380115, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene FRAS1-related extracellular matrix protein 3-like Neighboring gene FRAS1 related extracellular matrix 3 Neighboring gene GRB2 associated binding protein 1 Neighboring gene uncharacterized LOC101906545 Neighboring gene transfer RNA lysine (anticodon UUU)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryos†. Shi Y, et al. Biol Reprod, 2021 Aug 3. PMID 33899080
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryosdagger.
      Title: Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryos†.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC160027

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
    Names
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105416.1 → NP_001098886.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

      See identical proteins and their annotated locations for NP_001098886.1

      Status: PROVISIONAL

      Source sequence(s)
      BC153225
      UniProtKB/TrEMBL
      A7Z027, F1N052
      Related
      ENSBTAP00000067943.2, ENSBTAT00000070441.2
      Conserved Domains (8) summary
      smart00717
      Location:842 → 883
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00046
      Location:200 → 339
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:844 → 883
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00176
      Location:183 → 463
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:482 → 597
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:743 → 828
      HAND; HAND
      pfam09111
      Location:898 → 1010
      SLIDE; SLIDE
      pfam13892
      Location:81 → 107
      DBINO; DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14342538..14380115 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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