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    CPN1 carboxypeptidase N subunit 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 536753, updated on 4-Oct-2024

    Summary

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    Official Symbol
    CPN1provided by VGNC
    Official Full Name
    carboxypeptidase N subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:27656
    See related
    Ensembl:ENSBTAG00000023941
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CPN1 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (20960047..20993503, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene dynamin binding protein Neighboring gene small Cajal body-specific RNA 17 Neighboring gene small Cajal body-specific RNA 18 Neighboring gene U6 spliceosomal RNA Neighboring gene cytochrome P450 family 2 subfamily C member 23 Neighboring gene ER lipid raft associated 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC128810

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carboxypeptidase N catalytic chain
    Names
    CPN
    carboxypeptidase N small subunit
    carboxypeptidase N, polypeptide 1
    NP_001069548.1
    XP_010818211.1
    XP_010818212.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076080.2 → NP_001069548.1  carboxypeptidase N catalytic chain precursor

      See identical proteins and their annotated locations for NP_001069548.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105475
      UniProtKB/Swiss-Prot
      Q2KJ83
      Related
      ENSBTAP00000032859.4, ENSBTAT00000032932.6
      Conserved Domains (2) summary
      cd11308
      Location:341 → 415
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
      cl11393
      Location:24 → 337
      Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      20960047..20993503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010819909.3 → XP_010818211.1  carboxypeptidase N catalytic chain isoform X1

      Conserved Domains (1) summary
      cl11393
      Location:24 → 337
      Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins

    2. XM_010819910.3 → XP_010818212.1  carboxypeptidase N catalytic chain isoform X2

      Conserved Domains (2) summary
      cl11393
      Location:24 → 337
      Peptidase_M14_like; M14 family of metallocarboxypeptidases and related proteins
      cl21470
      Location:341 → 371
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KJ83.1 GenPept UniProtKB/Swiss-Prot:Q2KJ83

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