GNAQ G protein subunit alpha q [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: GNAQprovided by VGNC
Official Full Name: G protein subunit alpha qprovided by VGNC
Primary source: VGNC:VGNC:29453
See related: BGD:BT28266; Ensembl:ENSBTAG00000009789
Gene type: protein coding
RefSeq status: INFERRED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

Location:: chromosome: 8

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	8	NC_037335.1 (53685191..53995695, complement)

Chromosome 8 - NC_037335.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

atomic structure of GRK2 in complex with Galphaq and Gbetagamma, in which the activated Galpha subunit of Gq is fully dissociated from Gbetagamma and dramatically reoriented from its position in the inactive Galphabetagamma heterotrimer [g alphaq]
Title: Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

SHGC-143088 (e-PCR)
- UniSTS:171790

NoName (e-PCR)
- UniSTS:481018

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables G-protein beta/gamma-subunit complex binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables guanyl nucleotide binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in action potential	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phospholipase C-activating dopamine receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of heterotrimeric G-protein complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanine nucleotide-binding protein G(q) subunit alpha

Names: guanine nucleotide binding protein (G protein), q polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.