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    DSTYK dual serine/threonine and tyrosine protein kinase [ Bos taurus (domestic cattle) ]

    Gene ID: 534684, updated on 10-Aug-2024

    Summary

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    Official Symbol
    DSTYKprovided by VGNC
    Official Full Name
    dual serine/threonine and tyrosine protein kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:28227
    See related
    BGD:BT16849; Ensembl:ENSBTAG00000016618
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    RIPK5
    Orthologs
    human mouse all
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    Genomic context

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    See DSTYK in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (2925348..2985165, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene RB binding protein 5, histone lysine methyltransferase complex subunit Neighboring gene uncharacterized LOC112441810 Neighboring gene uncharacterized LOC132342435 Neighboring gene transmembrane and coiled-coil domain family 2 Neighboring gene NUAK family kinase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain. Peng J, et al. Biochim Biophys Acta, 2006 Nov-Dec. PMID 17123648, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual serine/threonine and tyrosine protein kinase
    Names
    dusty PK
    dusty protein kinase
    receptor interacting protein kinase 5
    receptor-interacting serine/threonine-protein kinase 5
    NP_001019995.1
    XP_024832106.1
    XP_059731426.1
    XP_059731427.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024824.1 → NP_001019995.1  dual serine/threonine and tyrosine protein kinase

      See identical proteins and their annotated locations for NP_001019995.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ054504
      UniProtKB/Swiss-Prot
      Q4TVR5
      UniProtKB/TrEMBL
      A0AAA9T182
      Related
      ENSBTAP00000022108.4, ENSBTAT00000022108.5
      Conserved Domains (2) summary
      smart00220
      Location:652 → 896
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd13975
      Location:650 → 911
      PKc_Dusty; Catalytic domain of the Dual-specificity Protein Kinase, Dusty

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2925348..2985165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059875444.1 → XP_059731427.1  dual serine/threonine and tyrosine protein kinase isoform X3

      UniProtKB/TrEMBL
      A0AAA9RV18

    2. XM_059875443.1 → XP_059731426.1  dual serine/threonine and tyrosine protein kinase isoform X1

      UniProtKB/TrEMBL
      A0AAA9T182

    3. XM_024976338.2 → XP_024832106.1  dual serine/threonine and tyrosine protein kinase isoform X2

      UniProtKB/TrEMBL
      A0AAA9RV18, A0AAA9SI00
      Related
      ENSBTAP00000085857.1, ENSBTAT00000108775.1
      Conserved Domains (1) summary
      cl21453
      Location:650 → 783
      PKc_like; Protein Kinases, catalytic domain

    RNA

    1. XR_009490761.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4TVR5.1 GenPept UniProtKB/Swiss-Prot:Q4TVR5

    Gene LinkOut

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