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    SENP6 SUMO specific peptidase 6 [ Bos taurus (domestic cattle) ]

    Gene ID: 533853, updated on 4-Oct-2024

    Summary

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    Official Symbol
    SENP6provided by VGNC
    Official Full Name
    SUMO specific peptidase 6provided by VGNC
    Primary source
    VGNC:VGNC:52824
    See related
    BGD:BT28105; Ensembl:ENSBTAG00000005869
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SENP6 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (15242164..15385807)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 30A Neighboring gene uncharacterized LOC132346198 Neighboring gene filamin A interacting protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene protein BEX1-like Neighboring gene myosin VI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO-specific endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein desumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of kinetochore assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of spindle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sentrin-specific protease 6
    Names
    SUMO1/sentrin specific peptidase 6
    NP_001179719.2
    XP_005210725.1
    XP_005210726.1
    XP_005210727.1
    XP_005210728.1
    XP_005210729.1
    XP_005210730.1
    XP_024852483.1
    XP_059745749.1
    XP_059745750.1
    XP_059745751.1
    XP_059745752.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192790.4 → NP_001179719.2  sentrin-specific protease 6

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000009
      Conserved Domains (1) summary
      cl23802
      Location:681 → 806
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      15242164..15385807
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005210668.5 → XP_005210725.1  sentrin-specific protease 6 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TGF0
      Related
      ENSBTAP00000097635.1, ENSBTAT00000123064.1
      Conserved Domains (2) summary
      COG5160
      Location:694 → 806
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:1006 → 1082
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    2. XM_005210671.5 → XP_005210728.1  sentrin-specific protease 6 isoform X5

      Conserved Domains (1) summary
      COG5160
      Location:694 → 806
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]

    3. XM_005210669.5 → XP_005210726.1  sentrin-specific protease 6 isoform X2

      Conserved Domains (2) summary
      COG5160
      Location:693 → 805
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:1005 → 1081
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    4. XM_005210670.5 → XP_005210727.1  sentrin-specific protease 6 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LVE8
      Related
      ENSBTAP00000059269.2, ENSBTAT00000084133.2
      Conserved Domains (2) summary
      COG5160
      Location:687 → 799
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:999 → 1075
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    5. XM_059889769.1 → XP_059745752.1  sentrin-specific protease 6 isoform X7

    6. XM_059889766.1 → XP_059745749.1  sentrin-specific protease 6 isoform X4

      UniProtKB/TrEMBL
      F1N1L7
      Related
      ENSBTAP00000007718.7, ENSBTAT00000007718.7

    7. XM_024996715.2 → XP_024852483.1  sentrin-specific protease 6 isoform X4

      UniProtKB/TrEMBL
      F1N1L7
      Conserved Domains (2) summary
      COG5160
      Location:590 → 702
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:902 → 978
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    8. XM_059889767.1 → XP_059745750.1  sentrin-specific protease 6 isoform X4

      UniProtKB/TrEMBL
      F1N1L7

    9. XM_059889768.1 → XP_059745751.1  sentrin-specific protease 6 isoform X6

    10. XM_005210672.5 → XP_005210729.1  sentrin-specific protease 6 isoform X6

      See identical proteins and their annotated locations for XP_005210729.1

      Conserved Domains (2) summary
      COG5160
      Location:512 → 624
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:824 → 900
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    11. XM_005210673.5 → XP_005210730.1  sentrin-specific protease 6 isoform X6

      See identical proteins and their annotated locations for XP_005210730.1

      Conserved Domains (2) summary
      COG5160
      Location:512 → 624
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:824 → 900
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

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