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    PSME4 proteasome activator subunit 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 528142, updated on 10-Oct-2024

    Summary

    Official Symbol
    PSME4provided by VGNC
    Official Full Name
    proteasome activator subunit 4provided by VGNC
    Primary source
    VGNC:VGNC:33476
    See related
    BGD:BT15703; Ensembl:ENSBTAG00000020262
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See PSME4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (36572842..36673076, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene G protein-coupled receptor 75 Neighboring gene uncharacterized LOC132346573 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene acylphosphatase 2 Neighboring gene TSPY like 6

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lysine-acetylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables peptidase activator activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables proteasome binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteasomal ubiquitin-independent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of spermatoproteasome complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    proteasome activator complex subunit 4
    Names
    proteasome (prosome, macropain) activator subunit 4
    proteasome activator PA200

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205952.1NP_001192881.1  proteasome activator complex subunit 4

      See identical proteins and their annotated locations for NP_001192881.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000011
      UniProtKB/Swiss-Prot
      F1MKX4
      Related
      ENSBTAP00000027001.6, ENSBTAT00000027001.6
      Conserved Domains (3) summary
      pfam11919
      Location:17571842
      DUF3437; Domain of unknown function (DUF3437)
      pfam16507
      Location:330828
      BLM10_mid; Proteasome-substrate-size regulator, mid region
      sd00044
      Location:16421671
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36572842..36673076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891311.1XP_059747294.1  proteasome activator complex subunit 4 isoform X1